... to be required for nephron induction, also instructs the nephron axis such that glomeruli differentiate in regions farthest from the source of Wnt. Kidney development Nephron patterning Glomerulus Mesonephros Chick embryo Wnt signaling The kidney is a vital, bilateral organ that is the central...

... of a polarised renal vesicle that differentiates into a comma-shaped body and then a regionalised S-shaped body (SSB), with the main prospective segments mapped to discrete domains. The regulatory circuits involved in initial nephron patterning are poorly understood. We report here that HNF1B, a transcription...