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Keywords: Nephrogenic mesenchyme
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Journal Articles
Journal: Development
Development (2015) 142 (11): 1937–1947.
Published: 1 June 2015
... Nephrogenic mesenchyme Pluripotent stem cell Ureteric bud Stem cells At the end of 2013, the global number of individuals being treated for end-stage renal disease (ESRD) was estimated at ∼3.2 million, with a 6.3% annual growth rate; significantly higher than the world population growth rate (1.1...
Journal Articles
Journal: Development
Development (2011) 138 (23): 5099–5112.
Published: 1 December 2011
... signaling through RAS. * Author for correspondence ( oxburl@mmc.org ) Competing interests statement The authors declare no competing financial interests. 26 9 2011 © 2011. Nephrogenic mesenchyme Cap mesenchyme GUDMAP Sprouty EGF FGF TGFα Mouse...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (18): 4593–4605.
Published: 15 September 2004
... of TGFβsignaling. Using a HoxB7cre transgene expressed in ureteric bud and collecting duct, we find that development of the collecting duct is Smad4 independent. By contrast, removal of Smad4 in nephrogenic mesenchyme using the Bmp7 cre/+ allele leads to disorganization of the nephrogenic mesenchyme and impairment...
Includes: Supplementary data