... is crucial for understanding the process of regeneration. Planarians are powerful model system to study regeneration and stem cell (neoblast) function. Here, using planaria, we show that the initial events of regeneration, such as epithelialization and epidermal organization are critically regulated...

... 2016 Summary: The response of planarian neoblasts to DNA damage differs according to their location, with both cell autonomous and non-autonomous mechanisms contributing to these regional differences. Stem cells DNA damage Planarian Neoblast Rad51 The proliferative response...

...Peter W. Reddien Planarians are flatworms capable of regenerating all body parts. Planarian regeneration requires neoblasts, a population of dividing cells that has been studied for over a century. Neoblast progeny generate new cells of blastemas, which are the regenerative outgrowths at wounds...

... programs that share a common evolutionary origin. * Author for correspondence ( [email protected] ) Competing interests statement The authors declare no competing financial interests. 15 8 2011 © 2011. Kidney Neoblast Planarian Protonephridia Regeneration...

...Jaume Baguñà; Emili Saló; Carme Auladell ABSTRACT In most regenerating systems, blastema cells arise by dedifferentiation of functional tissue cells. In planarians, though, it is still debatable whether dedifferentiated cells or a population of undifferentiated cells, the neoblasts, are the main...