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Keywords: Ndst
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Journal Articles

Bud specific N-sulfation of heparan sulfate regulates Shp2 -dependent FGF signaling during lacrimal gland induction

Yi Pan, Christian Carbe, Andrea Powers, Eric E. Zhang, Jeffrey D. Esko, Kay Grobe, Gen-Sheng Feng, Xin Zhang
Journal: Development
Development (2008) 135 (2): 301–310.
https://doi.org/10.1242/dev.014829
Published: 15 January 2008
...Yi Pan; Christian Carbe; Andrea Powers; Eric E. Zhang; Jeffrey D. Esko; Kay Grobe; Gen-Sheng Feng; Xin Zhang Preferential outgrowth of the bud cells forms the basis of branching morphogenesis. Here, we show that lacrimal gland development requires specific modification of heparan sulfates by Ndst...
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Journal Articles

Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development

Yi Pan, Andrea Woodbury, Jeffrey D. Esko, Kay Grobe, Xin Zhang
Journal: Development
Development (2006) 133 (24): 4933–4944.
https://doi.org/10.1242/dev.02679
Published: 15 December 2006
... of phospho-Erk and ERM were also downregulated in Ndst1 -mutant lenses. Taken together, these results establish an important role of Ndst1 function in FGF signaling during lens development. * Author for correspondence (e-mail: [email protected] ) 4 10 2006 © 2006. 2006 Ndst HSPG BMP...
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