...Sujata Bhattacharyya; Marianne Bronner-Fraser The nasal placode shares a common origin with other sensory placodes within a pre-placodal domain at the cranial neural plate border. However, little is known about early events in nasal placode development as it segregates from prospective lens, neural...

... , or genes regulating it, are possible targets for Pax-6. 31 01 19925 © 1997 by Company of Biologists 1997 Pax-6 Small eye craniofacial development optic vesicle nasal placode lens placode mouse Pax-6 , independently isolated by homology to gooseberry distal ( Walther...

... have found extensive similarities between the nasal lens placodes in their Pax-6 expression and Sey/Sey mutant phenotype. Like the lens placode, the nasal placode normally expresses Pax-6 mRNA and fails to form in Sey/Sey mutants. Similarly Pax-6 mRNA expression turns off throughout the nasal...

... (27×10 3 M r , connexin 32) and heart (43×10 3 M r , connexin 43). Immunolocalization with antibodies to the rat liver gap junction protein (27 ×10 3 M r ) demonstrated a ubiquitous and uniform distribution in all regions of the epithelium and mesenchyme except the nasal placode. In the placodal...

... at early stages to the thickened nasal placode and surrounding head ectoderm and then become progressively restricted to the olfactory domain. The expression of these characteristics appears to be modulated during development rather than being cell autonomous. The distribution of keratan sulphate...

... by Company of Biologists 1988 Small eye ( Sey ) eye nose developmental mutation optic vesicle lens placode nasal placode It will be clear to readers of this volume that the morphogenesis of the vertebrate head involves a complex series of reciprocal interactions between different cell...