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1-6 of 6
Keywords: Naïve pluripotency
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Journal Articles
Wilhelm Bouchereau, Luc Jouneau, Catherine Archilla, Irène Aksoy, Anais Moulin, Nathalie Daniel, Nathalie Peynot, Sophie Calderari, Thierry Joly, Murielle Godet, Yan Jaszczyszyn, Marine Pratlong, Dany Severac, Pierre Savatier, Véronique Duranthon, Marielle Afanassieff, Nathalie Beaujean
Journal:
Development
Development (2022) 149 (17): dev200538.
Published: 12 September 2022
... continuum in rabbit preimplantation embryos, and identified novel markers of naive pluripotency that might be instrumental for deriving naive pluripotent stem cell lines. Although the rabbit is evolutionarily closer to mice than to primates, we found that the transcriptome of rabbit epiblast cells shares...
Includes: Supplementary data
Journal Articles
Rebecca A. Lea, Afshan McCarthy, Stefan Boeing, Todd Fallesen, Kay Elder, Phil Snell, Leila Christie, Sarah Adkins, Valerie Shaikly, Mohamed Taranissi, Kathy K. Niakan
Journal:
Development
Development (2021) 148 (22): dev199378.
Published: 12 November 2021
... and that KLF17 can drive transgene-mediated resetting to naïve pluripotency. This implies a role for KLF17 in establishing naïve pluripotency. However, CRISPR-Cas9-mediated knockout studies reveal that KLF17 is not required for naïve pluripotency acquisition in vitro . Transcriptome analysis of naïve hESCs...
Includes: Supplementary data
Journal Articles
Madeleine Linneberg-Agerholm, Yan Fung Wong, Jose Alejandro Romero Herrera, Rita S. Monteiro, Kathryn G. V. Anderson, Joshua M. Brickman
Journal:
Development
Development (2019) 146 (24): dev180620.
Published: 16 December 2019
... primitive endoderm (PrE), the blastocyst-stage progenitor of the extra-embryonic endoderm. Here, we apply this context dependency to human ESCs, showing that activation of Nodal and Wnt signalling drives the differentiation of naïve pluripotent cells toward extra-embryonic PrE, or hypoblast, and these can...
Includes: Supplementary data
Journal Articles
Haisong Wang, Wenhao Zhang, Jian Yu, Congyu Wu, Qian Gao, Xu Li, Yanni Li, Jinxin Zhang, Yaru Tian, Tao Tan, Weizhi Ji, Luyuan Li, Yang Yu, Ling Shuai
Journal:
Development
Development (2018) 145 (11): dev160531.
Published: 11 June 2018
.... , Viukov , S. , Maza , I. , Zviran , A. , et al. ( 2013 ). Derivation of novel human ground state naive pluripotent stem cells . Nature 504 , 282 - 286 . 10.1038/nature12745 Gao , Q. , Zhang , W. , Ma , L. , Li , X. , Wang , H. , Li , Y. , Freimann , R...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2017) 144 (2): 175–186.
Published: 15 January 2017
...Thorsten Boroviak; Jennifer Nichols ABSTRACT Naïve pluripotent mouse embryonic stem cells (ESCs) resemble the preimplantation epiblast and efficiently contribute to chimaeras. Primate ESCs correspond to the postimplantation embryo and fail to resume development in chimaeric assays. Recent data...
Journal Articles
Tankyrase inhibition promotes a stable human naïve pluripotent state with improved functionality
FreeLudovic Zimmerlin, Tea Soon Park, Jeffrey S. Huo, Karan Verma, Sarshan R. Pather, C. Conover Talbot, Jr., Jasmin Agarwal, Diana Steppan, Yang W. Zhang, Michael Considine, Hong Guo, Xiufeng Zhong, Christian Gutierrez, Leslie Cope, M. Valeria Canto-Soler, Alan D. Friedman, Stephen B. Baylin, Elias T. Zambidis
Journal:
Development
Development (2016) 143 (23): 4368–4380.
Published: 1 December 2016
.... Zambidis The derivation and maintenance of human pluripotent stem cells (hPSCs) in stable naïve pluripotent states has a wide impact in human developmental biology. However, hPSCs are unstable in classical naïve mouse embryonic stem cell (ESC) WNT and MEK/ERK signal inhibition (2i) culture. We show...
Includes: Supplementary data
