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Keywords: NURF
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Journal Articles

A multi-gene knockdown approach reveals a new role for Pax6 in controlling organ number in Drosophila

Alison J. Ordway, Gary M. Teeters, Bonnie M. Weasner, Brandon P. Weasner, Robert Policastro, Justin P. Kumar
Journal: Development
Development (2021) 148 (9): dev198796.
https://doi.org/10.1242/dev.198796
Published: 13 May 2021
... downregulation of Pax6 with either the NURF nucleosome remodeling complex or the Pointed transcription factor transforms the head epidermis into an antenna. This is a previously unidentified fate change that is also not observed with the loss of individual genes. We propose that the use of multi-gene knockdowns...
View article titled, A multi-gene knockdown approach reveals a new role for Pax6 in controlling organ number in Drosophila
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Includes: Supplementary data
Journal Articles

C. elegans ISWI and NURF301 antagonize an Rb-like pathway in the determination of multiple cell fates

Erik C. Andersen, Xiaowei Lu, H. Robert Horvitz
Journal: Development
Development (2006) 133 (14): 2695–2704.
https://doi.org/10.1242/dev.02444
Published: 15 July 2006
... encodes the C. elegans homolog of Drosophila melanogaster ISWI. The C. elegans ISW-1 protein likely acts as part of a Nucleosome Remodeling Factor (NURF) complex with NURF-1, a nematode ortholog of NURF301, to promote the synMuv phenotype. isw-1 and nurf-1 mutations suppress both the synMuv phenotype...
View article titled, C. elegans ISWI and NURF301 antagonize an Rb-like pathway in the determination of multiple cell fates
Open the PDF for C. elegans ISWI and NURF301 antagonize an Rb-like pathway in the determination of multiple cell fates in another window
Includes: Supplementary data