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Keywords: NT3
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Journal Articles
Journal: Development
Development (2003) 130 (15): 3535–3545.
Published: 1 August 2003
... neurotrophic factors previously reported to prevent the degeneration of lesioned adult central noradrenergic neurons, GDNF and neurotrophin 3 (NT3), do not play significant roles in the prenatal development of locus coeruleus noradrenergic neurons, as demonstrated by: (1)the lack of alterations in double Gdnf...
Journal Articles
Journal: Development
Development (2003) 130 (8): 1479–1491.
Published: 15 April 2003
.... Neurotrophin specificity has been attributed to the selective expression of the Trk tyrosine kinase receptors in different neuronal subpopulations. However, despite overlapping expression of TrkB and TrkC in many sensory ganglia, brain-derived neurotrophic factor (BDNF) and neurotrophin 3 (NT3) null mutant...
Journal Articles
Journal: Development
Development (2001) 128 (21): 4315–4327.
Published: 1 November 2001
... (NT3) ablation in mice causes a more severe neuronal phenotype than deletion of its receptor TrkC, suggesting that NT3 acts also through other non-preferred Trk receptors. To study the role of low-affinity ligand receptor interactions in vivo, we have replaced the Nt3 gene with the gene for brain...