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Keywords: NPC
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Journal Articles

NPC1 deficiency impairs cerebellar postnatal development of microglia and climbing fiber refinement in a mouse model of Niemann–Pick disease type C

Open Access
Bridget R. Boyle, Sierra E. Melli, Ruth S. Altreche, Zachary M. Padron, Fawad A. K. Yousufzai, Sarah Kim, Mariella D. Vasquez, Dawn M. Carone, Benjamin R. Carone, Ileana Soto
Journal: Development
Development (2020) 147 (21): dev189019.
https://doi.org/10.1242/dev.189019
Published: 3 August 2020
... and whether these effects contribute to neurodegeneration in Niemann–Pick disease type C (NPC). Degeneration of cerebellar Purkinje cells occurs at an earlier stage and to a greater extent in NPC; therefore, we analyzed the effect of NPC1 deficiency on microglia and on climbing fiber synaptic refinement...
View article titled, NPC1 deficiency impairs cerebellar postnatal development of microglia and climbing fiber refinement in a mouse model of Niemann–Pick disease type C
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Includes: Supplementary data
Journal Articles

Single-cell mechanical phenotype is an intrinsic marker of reprogramming and differentiation along the mouse neural lineage

Free
Marta Urbanska, Maria Winzi, Katrin Neumann, Shada Abuhattum, Philipp Rosendahl, Paul Müller, Anna Taubenberger, Konstantinos Anastassiadis, Jochen Guck
Journal: Development
Development (2017) 144 (23): 4313–4321.
https://doi.org/10.1242/dev.155218
Published: 1 December 2017
... by The Company of Biologists Ltd 2017 http://www.biologists.com/user-licence-1-1/ Summary: Stiffening accompanies reprogramming of murine fetal neural progenitor cells towards pluripotency and is reversed in neural differentiation of pluripotent cells. Cell mechanics Pluripotency iPSC NPC...
View article titled, Single-cell mechanical phenotype is an intrinsic marker of reprogramming and differentiation along the mouse neural lineage
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Includes: Supplementary data
Journal Articles

The nucleoporin Seh1 forms a complex with Mio and serves an essential tissue-specific function in Drosophila oogenesis

Free
Stefania Senger, John Csokmay, Tanveer Akbar, Takako Iida Jones, Prabuddha Sengupta, Mary A. Lilly
Journal: Development
Development (2011) 138 (10): 2133–2142.
https://doi.org/10.1242/dev.057372
Published: 15 May 2011
...Stefania Senger; John Csokmay; Tanveer Akbar; Takako Iida Jones; Prabuddha Sengupta; Mary A. Lilly The nuclear pore complex (NPC) mediates the transport of macromolecules between the nucleus and cytoplasm. Recent evidence indicates that structural nucleoporins, the building blocks of the NPC, have...
View article titled, The nucleoporin Seh1 forms a complex with Mio and serves an essential tissue-specific function in Drosophila oogenesis
Open the PDF for The nucleoporin Seh1 forms a complex with Mio and serves an essential tissue-specific function in Drosophila oogenesis in another window
Includes: Supplementary data