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Keywords: N-cadherin
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Journal Articles
Journal: Development
Development (2018) 145 (5): dev149823.
Published: 08 March 2018
...Alexia Vite; Caimei Zhang; Roslyn Yi; Sabrina Emms; Glenn L. Radice ABSTRACT Shortly after birth, muscle cells of the mammalian heart lose their ability to divide. At the same time, the N-cadherin/catenin cell adhesion complex accumulates at the cell termini, creating a specialized type of cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (13): 2456–2468.
Published: 01 July 2017
... essential for NC migration in amphibians and zebrafish by controlling cell polarity in a cell contact-dependent manner. Cell contact during CIL requires the participation of the cell adhesion molecule N-cadherin, which starts to be expressed by NC cells as a consequence of the switch between E- and N...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (22): 4510–4521.
Published: 15 November 2013
... interkinetic nuclear migration, but mitosis of retinal progenitors occurs in situ . Rapidly dividing retinal progenitors form neurogenic clusters tightly associated with Alcama/N-cadherin-labeled Müller glial radial processes. Genetic suppression of N-cadherin function interferes with basal migration of...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (16): 2691–2701.
Published: 15 August 2010
...Ki-Sook Park; Barry M. Gumbiner The development of neural crest cells involves an epithelial-mesenchymal transition (EMT) associated with the restriction of cadherin 6B expression to the pre-migratory neural crest cells (PMNCCs), as well as a loss of N-cadherin expression. We find that cadherin 6B...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (12): 1981–1990.
Published: 15 June 2010
... induce some of these changes in NC adhesion and also promote specification of NC-derived pigment cells. Here, we show that the zebrafish transcription factor Ovo1 is a Wnt target gene that controls migration of pigment precursors by regulating the intracellular movements of N-cadherin (Ncad). Ovo1...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (8): 1315–1325.
Published: 15 April 2010
... that nectin-2, an immunoglobulin-like cell adhesion molecule, is involved in the neurulation of Xenopus embryos in cooperation with N-cadherin. First, we found that, at the beginning of neurulation, nectin-2 was strongly expressed in the superficial cells of neuroepithelium. The knockdown of nectin -2...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (21): 3521–3530.
Published: 01 November 2008
... soaked in PDGFA elicit a directional attractive movement response in mesoderm cells, showing that PDGFA can provide directional information. Surprisingly, however, PDGF signalling is also required for directional movement towards other attractants, such as FGF4. PDGF signalling controls N-cadherin...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (1): 31–41.
Published: 01 January 2007
... introduced N-cadherin cDNA into the E-cadherin genomic locus. We show that the expression of N-cadherin driven from the E-cadherin locus reflects the expression pattern of endogenous E-cadherin. Heterozygous mice co-expressing E- and N-cadherin are vital and show normal embryonic development. Interestingly...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (24): 4839–4847.
Published: 15 December 2006
... investigate the function of two families of molecules that are thought to regulate cell sorting and aggregation. By blocking Eph/ephrins or N-cadherin function, we measure changes in neural crest cell migratory behaviors that lead to alterations in sympathetic ganglia formation using a recently developed...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (5): 953–963.
Published: 01 March 2005
... of layer selection. We observed that R8, R7 and L1-L5 afferents target to their temporary layers independently,suggesting that afferent-target, but not afferent-afferent, interactions dictate the targeting specificity. N-cadherin is required in the first stage for R7 growth cones to reach and remain...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2002) 129 (14): 3281–3294.
Published: 15 July 2002
...Zsolt Lele; Anja Folchert; Miguel Concha; Gerd-Jörg Rauch; Robert Geisler; Frédéric Rosa; Steve W. Wilson; Matthias Hammerschmidt; Laure Bally-Cuif N-cadherin (Ncad) is a classical cadherin that is implicated in several aspects of vertebrate embryonic development, including somitogenesis, heart...