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Keywords: N-cadherin
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Neural development
Journal: Development
Development (2023) 150 (16): dev201651.
Published: 24 August 2023
... observed with N-cadherin at the AJs of the apical border along the SC, it was also present in most basal locations in the dorsal VZ and the cell bodies of the most dorsal Robo3-expressing neurons ( Fig. 6 C,C′). β-catenin protein was very abundant in the commissure, as was Robo3 ( Fig. 6 C″). In agreement...
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Journal: Development
Development (2018) 145 (5): dev149823.
Published: 8 March 2018
...Alexia Vite; Caimei Zhang; Roslyn Yi; Sabrina Emms; Glenn L. Radice ABSTRACT Shortly after birth, muscle cells of the mammalian heart lose their ability to divide. At the same time, the N-cadherin/catenin cell adhesion complex accumulates at the cell termini, creating a specialized type of cell...
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Journal: Development
Development (2010) 137 (16): 2691–2701.
Published: 15 August 2010
...Ki-Sook Park; Barry M. Gumbiner The development of neural crest cells involves an epithelial-mesenchymal transition (EMT) associated with the restriction of cadherin 6B expression to the pre-migratory neural crest cells (PMNCCs), as well as a loss of N-cadherin expression. We find that cadherin 6B...
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Journal: Development
Development (2010) 137 (12): 1981–1990.
Published: 15 June 2010
... induce some of these changes in NC adhesion and also promote specification of NC-derived pigment cells. Here, we show that the zebrafish transcription factor Ovo1 is a Wnt target gene that controls migration of pigment precursors by regulating the intracellular movements of N-cadherin (Ncad). Ovo1...
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Journal: Development
Development (2007) 134 (1): 31–41.
Published: 1 January 2007
... introduced N-cadherin cDNA into the E-cadherin genomic locus. We show that the expression of N-cadherin driven from the E-cadherin locus reflects the expression pattern of endogenous E-cadherin. Heterozygous mice co-expressing E- and N-cadherin are vital and show normal embryonic development. Interestingly...
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Journal Articles
Journal: Development
Development (2006) 133 (24): 4839–4847.
Published: 15 December 2006
... investigate the function of two families of molecules that are thought to regulate cell sorting and aggregation. By blocking Eph/ephrins or N-cadherin function, we measure changes in neural crest cell migratory behaviors that lead to alterations in sympathetic ganglia formation using a recently developed...
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Journal: Development
Development (1996) 122 (9): 2895–2902.
Published: 1 September 1996
... in the establishment and maintenance of islet architecture in the mouse. Furthermore, NCAM was expressed on the cell surface of β-cells lacking Eand N-cadherin, indicating that NCAM does not function as an essential CAM between pancreatic β-cells. In none of the previous in vivo studies of cadherin function...
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Journal: Development
Development (1990) 110 (1): 97–104.
Published: 1 September 1990
...Toshihiko Fujimori; Seiji Miyatani; Masatoshi Takeichi Xenopus embryos express N-cadherin in a pattern similar to that observed in other species, and cells expressing Xenopus N-cadherin can bind to cells expressing chicken N-cadherin in vitro . To investigate the developmental role of this molecule...