.... † Authors for correspondence (e-mail: [email protected] ; [email protected] ) * Present address: 1550 4th Street, Rock Hall, Room RH 282C, UCSF at Mission Bay, San Francisco, CA 94143, USA 3 7 2006 © 2006. 2006 Myogenic induction Myf5 activation Wnt β-catenin Frizzled...

... vector and used as a feeder layer for the somite cultures. * Author for correspondence (e-mail: [email protected] ) 27 07 1998 07 09 1999 © 1999 by Company of Biologists 1999 Myogenic induction MyoD Myf5 activation Wnt Frzb1 There is increasing evidence...

... 1998 © 1998 by Company of Biologists 1998 Myogenic induction MyoD Myf5 Wnt Sonic Hedgehog Skeletal muscles of the body are derived from segmental mesodermal structures called somites. Shortly after their formation, somites give rise dorsally to the epithelial dermomyotome...

... of paraxial mesoderm, lead to activation of myf-5 , while signals derived from the dorsal ectoderm lead to activation of MyoD laterally; in this case, however, differentiation is probably repressed by signals originating from lateral mesoderm. This information is summarized in a model of myogenic induction...