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Keywords: Myocardial infarction
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Journal Articles

Pitx2 maintains mitochondrial function during regeneration to prevent myocardial fat deposition

Available to Purchase
Lele Li, Ge Tao, Matthew C. Hill, Min Zhang, Yuka Morikawa, James F. Martin
Journal: Development
Development (2018) 145 (18): dev168609.
https://doi.org/10.1242/dev.168609
Published: 26 September 2018
... protects mature cardiomyocytes from ischemic injury and promotes heart repair. Here, we characterized the long-term myocardial phenotype following myocardial infarction (MI) in Pitx2 conditional-knockout ( Pitx2 CKO) mice. We found adipose-like tissue in Pitx2 CKO hearts 60 days after MI induced surgically...
View articletitled, Pitx2 maintains mitochondrial function during regeneration to prevent myocardial fat deposition
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Includes: Supplementary data
Journal Articles

Wnt inhibition promotes vascular specification of embryonic cardiac progenitors

Open Access
David E. Reichman, Laura Park, Limor Man, David Redmond, Kenny Chao, Richard P. Harvey, Makoto M. Taketo, Zev Rosenwaks, Daylon James
Journal: Development
Development (2018) 145 (1): dev159905.
https://doi.org/10.1242/dev.159905
Published: 8 January 2018
... inhibitory Wnt signaling via Wnt5a fosters endothelial differentiation of Nkx2.5 + cardiac progenitor cells during mouse embryogenesis and human pluripotent stem cell differentiation. Cardiac development Cardiac differentiation Wound healing Myocardial infarction Myocardial scar formation...
View articletitled, Wnt inhibition promotes vascular specification of embryonic cardiac progenitors
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Includes: Supplementary data