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Keywords: Muscular dystrophy
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Journal Articles
Journal: Development
Development (2022) 149 (8): dev200112.
Published: 25 March 2022
... in skeletal muscle regeneration and, in the absence of eosinophil-secreted interleukin (IL) 4 and IL13, fibro-adipogenic progenitors fail to support muscle stem cell proliferation. However, the role of eosinophils in muscular dystrophy remains elusive. Although it has been shown that eosinophils are present...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (12): 2104–2122.
Published: 15 June 2017
... function is a hallmark of a number of conditions, ranging from developmental disorders to rhabdomyosarcoma and muscular dystrophies ( Emery, 2002 ). In the adult, acute muscle injury such as volumetric loss, late-onset muscle dystrophies, neuromuscular degenerative diseases, cachexia as well as aging...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (8): 1375–1387.
Published: 15 April 2016
... by the oocyte. Drosophila Egg chamber Morphogenesis Muscular dystrophy Laminin Vitellogenesis When studying morphogenesis, it can often be difficult to tease apart the physical contributions that different cell types make to the form of a tissue or organ. The elongation of the Drosophila...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (22): 4602–4613.
Published: 15 November 2013
..., and defects in its structure correlate with a subset of muscular dystrophies. Col22a1 encodes the MTJ component collagen XXII, the function of which remains unknown. Here, we have cloned and characterized the zebrafish col22a1 gene and conducted morpholino-based loss-of-function studies in developing embryos...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (1): 136–146.
Published: 1 January 2013
...Mario Pantoja; Karin A. Fischer; Nicholas Ieronimakis; Morayma Reyes; Hannele Ruohola-Baker Duchenne muscular dystrophy is a lethal genetic disease characterized by the loss of muscle integrity and function over time. Using Drosophila , we show that dystrophic muscle phenotypes can be significantly...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (21): 3597–3606.
Published: 1 November 2009
... (EBD) uptake assays were performed as described previously ( Conti et al., 2008 ). Measurements of creatine kinase (CK) levels were performed by Antech Diagnostics (Irvine, CA, USA). * Author for correspondence( umueller@scripps.edu ) Integrin Talin Muscular dystrophy Dystrophin...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (19): 3367–3376.
Published: 1 October 2009
... and in the mature myotome and defects in its composition underlie certain forms of muscular dystrophy. A major component of this extracellular structure is the laminin polymer, which assembles into a resilient meshwork that protects the sarcolemma during contraction. Here we describe a zebrafish mutant, softy...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (11): 2043–2053.
Published: 1 June 2008
... force generation by skeletal muscle. * Author for correspondence (e-mail: umueller@scripps.edu ) 31 3 2008 © 2008. 2008 Integrin Talin Muscular dystrophy Myopathy Mouse Adhesion of muscle fibers to the extracellular matrix (ECM) is essential for skeletal muscle...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (23): 5851–5860.
Published: 1 December 2003
... of the human muscular dystrophies. Here, we show that one of these mutations, sapje , disrupts the zebrafish orthologue of the X-linked human Duchenne muscular dystrophy ( DMD ) gene. Mutations in this locus cause Duchenne or Becker muscular dystrophies in human patients and are thought to result...
Journal Articles
Journal: Development
Development (2002) 129 (14): 3505–3512.
Published: 15 July 2002
...Michael J. Parsons; Isabel Campos; Elizabeth M. A. Hirst; Derek L. Stemple Muscular dystrophy is frequently caused by disruption of the dystrophin-glycoprotein complex (DGC), which links muscle cells to the extracellular matrix. Dystroglycan, a central component of the DGC, serves as a laminin...