... on zonation within the kidney and association with various epithelial components ( England et al., 2020 ). Here, we find multiple instances of heterogeneity within the SPs and their mural cell derivatives in the developing kidney. Most intriguingly, we observe different levels of Klf4 protein in Foxd1...

... + , respectively. Other populations, such as Nes + mural cells, S100B + Schwann cells, and other non-stromal cells, were also identified. RNA velocity analysis suggested that a Plap-1 high Ly6a + cell population was the source of PDLCs. Lineage tracing of Plap-1 + PDLCs during periodontal injury showed periodontal...

... component, are crucial for these processes, yet the signaling pathway(s) that regulate their expression remain unknown. Here, we show that mural cells have active Wnt/β-catenin signaling during central nervous system development in mice. Bulk RNA sequencing and validation using postnatal day 10 and 14 wild...

...Elvin V. Leonard; Ricardo J. Figueroa; Jeroen Bussmann; Nathan D. Lawson; Julio D. Amigo; Arndt F. Siekmann ABSTRACT Vascular networks comprise endothelial cells and mural cells, which include pericytes and smooth muscle cells. To elucidate the mechanisms controlling mural cell recruitment during...