...Rita A. Batista; Liping Wang; Kenny A. Bogaert; Susana M. Coelho ABSTRACT The transition from simple to complex multicellularity represents a major evolutionary step that occurred in only a few eukaryotic lineages. Comparative analyses of these lineages provide insights into the molecular...

...Liang Bao; Junling Ren; Mary Nguyen; Arkadiusz Slawomir Slusarczyk; Julie M. Thole; Susana Perez Martinez; Jinling Huang; Tomomichi Fujita; Mark P. Running ABSTRACT A complete picture of how signaling pathways lead to multicellularity is largely unknown. Previously, we generated mutations...

...Iñaki Ruiz-Trillo; Alex de Mendoza ABSTRACT Almost all animals undergo embryonic development, going from a single-celled zygote to a complex multicellular adult. We know that the patterning and morphogenetic processes involved in development are deeply conserved within the animal kingdom. However...

... of extant multicellular animals, we suggest that this system can be explored to study the genetic features underlying the evolution of multicellularity and regeneration. * Author for correspondence ( [email protected] ) Handling Editor: Cassandra Extavour Competing interests The authors...

... the closest unicellular relatives of animals have provided important insights into the evolution of animal multicellularity. We know that the unicellular ancestor of animals had an unexpectedly complex genetic repertoire, including many genes that are key to animal development and multicellularity. Thus...