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Keywords: Msx2
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Journal Articles
Journal: Development
Development (2013) 140 (5): 1034–1044.
Published: 1 March 2013
... undifferentiated precursor cells located above the eye. Here, we demonstrate a role for Foxc1 in modulating the influence of Bmp signaling on the expression of Msx2 and the specification of these cells. Inactivation of Foxc1 results in a dramatic reduction in skull vault growth and causes an expansion of Msx2...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (21): 3577–3586.
Published: 1 November 2008
... cells (NCCs) that ultimately specifies cardiac NCC function for OFT development, but does not regulate NCC migration to the heart. We show that Pbx1 directly activates Pax3 , leading to repression of its target gene Msx2 in NCCs. Compound Msx2/Pbx1 -null embryos display significant rescue of cardiac...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (22): 4937–4950.
Published: 15 November 2005
...Mamoru Ishii; Jun Han; Hai-Yun Yen; Henry M. Sucov; Yang Chai; Robert E. Maxson, Jr The neural crest is a multipotent, migratory cell population that contributes to a variety of tissues and organs during vertebrate embryogenesis. Here, we focus on the function of Msx1 and Msx2 , homeobox genes...
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Journal Articles
Journal: Development
Development (2002) 129 (19): 4647–4660.
Published: 1 October 2002
...) Upregulation of Msx1 expression in frontonasal mass (arrow) and maxillary prominence. (D) Expression of Msx2 encompasses one-third of the maxillary prominence (lower arrow) and the lateral third of the frontonasal mass (upper arrow). Normal expression domain of Msx2 in the maxilla is restricted...
Journal Articles
Journal Articles
Journal: Development
Development (2001) 128 (11): 2075–2084.
Published: 1 June 2001
... for a positive influence of FGFs on BMP gene expression, the physiological implication of FGFs in apoptosis appears to result from their requirement for the expression of genes of the apoptotic cascade. We have identified MSX2 and Snail as candidate genes associated with apoptosis the expression of which...
Journal Articles
Journal Articles
Journal: Development
Development (1998) 125 (7): 1241–1251.
Published: 1 April 1998
... as craniosynostosis, presumably involves disturbance of these interactions. Mutations in the homeobox gene Msx2 as well as the FGF receptors cause human craniosynostosis syndromes. Our histological analysis of mouse calvarial development demonstrated morphological differences in the sagittal suture between embryonic...
Journal Articles
Journal: Development
Development (1995) 121 (4): 1065–1076.
Published: 1 April 1995
...Angela D. Reginelli; Yao-Qi Wang; David Sassoon; Ken Muneoka ABSTRACT We report that during mouse fetal development transcripts of Msx1 and Msx2 become progressively restricted to cells that will form more distal digit structures; the Msx2 expression domain is always more distal than Msx1...