.... , Wang , H. Y. , Hu , G. H. , Shen , M. M. and Abate-Shen , C. ( 1996 ). Comparison of Msx-1 and Msx-2 suggests a molecular basis for functional redundancy . Mech. Dev. 55 , 185 – 199 . 10.1016/0925-4773(96)00503-5 Chapman , D. L. , Garvey , N. , Hancock , S...

... these apoptotic events. In an effort to identify some of the genes that may be involved in the apoptotic pathway we show that Msx -2 is upregulated in the apoptotic neuroepithelium and thus may be involved, whereas Bmp-4 is not altered and thus presumably not involved. Since these apoptotic event take place...

...-4, msx-1 and msx-2 gene expression. When BMP-beads were implanted in the interdigital spaces, programmed cell death and the freeing of the digits were both accelerated. Implantation of beads bearing BMP-4 at the tip of the growing digits was followed by digit bifurcation, accompanied...

... degenerate. Wl and ll limb buds lack thickened AERs capable of promoting limb outgrowth, and their thin apical ectoderms fail to express the homeobox-containing gene Msx-2 , which is highly expressed by normal AERs and has been implicated in regulating AER activity. Here we report that exogenous IGF-I...