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Keywords: Morpholinos
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Journal Articles
Journal: Development
Development (2012) 139 (9): 1691–1699.
Published: 1 May 2012
...Alexandra Tallafuss; Dan Gibson; Paul Morcos; Yongfu Li; Steve Seredick; Judith Eisen; Philip Washbourne To understand the molecular mechanisms of development it is essential to be able to turn genes on and off at will and in a spatially restricted fashion. Morpholino oligonucleotides (MOs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (24): 5491–5502.
Published: 15 December 2005
... Kallmann Syndrome Neural crest Morpholinos To determine whether the reductions in gnrh3 and gnrh2 cell number caused by the injection of sox10 and foxd3 MOs were due to non-specific effects, we examined the expression of otx2,fgf8 and six4.1 in MO-injected embryos. The otx2 gene...
Journal Articles
Journal: Development
Development (2004) 131 (4): 851–862.
Published: 15 February 2004
... a new protocol allowing in vivo lipofection of antisense morpholino oligonucleotides into the retina. The resulting XSEB4R knockdown causes an impairment of neuronal differentiation, with an increase in the number of glial cells. By contrast, our gain-of-function analysis demonstrates that Xseb4R...