...Aude Porcher; Asmahan Abu-Arish; Sébastien Huart; Baptiste Roelens; Cécile Fradin; Nathalie Dostatni It is widely accepted that morphogenetic gradients determine cell identity by concentration-dependent activation of target genes. How precise is each step in the gene expression process that acts...

...Carlos Torroja; Nicole Gorfinkiel; Isabel Guerrero The Hedgehog (Hh) morphogenetic gradient controls multiple developmental patterning events in Drosophila and vertebrates. Patched (Ptc), the Hh receptor, restrains both Hh spreading and Hh signaling. We report how endocytosis regulates...

... and Institute of Molecular Genetics, Baylor College of Medicine, Texas Medical Center, Houston, TX 77030, USA 26 10 1990 © 1991 by Company of Biologists 1991 Drosophila segmentation morphogenetic gradients gap genes head development. The development of the anteroposterior...

... to organize, for instance, a leg disc with the concentrically arranged primordia of the leg segments as well as for the separation of the cells forming the imaginal disc from the cells forming the surrounding larval ectoderm. The term ‘morphogenetic gradient’ is used in the literature for two very...