.... Planar cell polarity Frizzled 6 Hair follicle Epidermis Morphogenesis Mouse National Institute of Child Health and Human Development http://dx.doi.org/10.13039/100000071 R00HD097298 R01HD105009 National Science Foundation http://dx.doi.org/10.13039/100000001 DGE-2039656...

..., shape and patterned gene expression in an organoid model of mammalian gastrulation. Gastruloid Morphogenesis Cell signaling National Science Foundation http://dx.doi.org/10.13039/100000001 1750663 2134935 Embryos undergo both dramatic physical transformations and complex...

... Morphogenesis Optogenetics Patterning National Institutes of Health http://dx.doi.org/10.13039/100000002 R01NS087253 Chan Zuckerberg Initiative http://dx.doi.org/10.13039/100014989 CZB-277B National Science Foundation http://dx.doi.org/10.13039/100000001...

... and self-organized flow of information during morphogenesis . Nat. Rev. Mol. Cell Biol. 22 , 245 - 265 . 10.1038/s41580-020-00318-6 Concha , M. L. and Reig , G. ( 2022 ). Origin, form and function of extraembryonic structures in teleost fishes . Phil. Trans. R. Soc. B Biol. Sci...

...Dina J. Ashour; Clinton H. Durney; Vicente J. Planelles-Herrero; Tim J. Stevens; James J. Feng; Katja Röper ABSTRACT During morphogenesis, large-scale changes of tissue primordia are coordinated across an embryo. In Drosophila , several tissue primordia and embryonic regions are bordered...

...Shinjini Ray; Priti Agarwal; Anat Nitzan; François Nédélec; Ronen Zaidel-Bar ABSTRACT Actin dynamics play an important role in tissue morphogenesis, yet the control of actin filament growth takes place at the molecular level. A challenge in the field is to link the molecular function of actin...

... morphogenesis, making embryonic membranes dispensable. In addition, two cell adhesion systems, the septate junction mediating adhesion of lateral cell membranes and the integrin-basement membrane adhesion systems, develop only in the late embryonic stages (stage 15 or later, Tepass and Hartenstein, 1994...

...Pei Zhang; Jiwei Chen; Xiangchuan Wang; Yingchao Geng; Liangyu Sun; Hongjie Zhang ABSTRACT Organ morphogenesis needs orchestration of a series of cellular events, including cell division, cell shape change, cell rearrangement and cell death. Cytokinesis, the final step of cell division, is involved...

...Jeremy B. A. Green ABSTRACT Morphogenesis is extremely diverse, but its systematic quantification to determine the physical mechanisms that produce different phenotypes is possible by quantifying the underlying cell behaviours. These are limited and definable: they consist of cell proliferation...

... its C terminus. The SRGP-1 C terminus is sufficient to target it to adherens junctions, but only during later embryonic morphogenesis, when junctional tension is known to increase. Surprisingly, mutations that disrupt stabilizing salt bridges in the M domain block this recruitment. Loss of SRGP-1...

... by neural plate morphogenesis. Finally, we show that an increase in surface ectoderm resistive forces is detrimental for neural plate morphogenesis. Efficient NTC is realized by the combined activities of CE and AC of neuroepithelial cells ( Wallingford and Harland, 2002 ; Haigo et al., 2003 ; Ybot...

... almost relentlessly, building plant architecture and morphogenesis. Boundary domains display reduced growth and orchestrate development of adjacent tissues in a non-cell-autonomous manner. How these two functions are achieved remains elusive despite the identification of several boundary-specific genes...

... ), indicating similar compensation mechanisms in higher vertebrates. On the other hand, Drosophila embryos lacking Smallish, the fly orthologue of Lmo7, are defective in epithelial morphogenesis ( Beati et al., 2018 ), pointing to the indispensable role of Smallish in actomyosin control. Double knockout...

... and shape the mammalian embryo. We detail how this can be complemented with precise measurements and manipulations of tissue biochemistry, mechanics and geometry across spatial and temporal scales to provide insights into the mechanochemical feedback loops governing embryo morphogenesis. Finally, we discuss...

...Satoshi Yamashita; Boris Guirao; François Graner ABSTRACT Within developing tissues, cell proliferation, cell motility and other cell behaviors vary spatially, and this variability gives a complexity to the morphogenesis. Recently, novel formalisms have been developed to quantify tissue deformation...

... morphogenesis. We injected KI cocktails containing Cas9 protein, gRNAs and repair donors into one-cell-stage embryos and visually screened embryos for fluorescence, comparing them with reported expression patterns of the endogenous transcripts ( Howe et al., 2021 ). We consistently observed expression...

...Brent H. Wyatt; Nirav M. Amin; Kristen Bagley; Dustin J. Wcisel; Michael K. Dush; Jeffrey A. Yoder; Nanette M. Nascone-Yoder ABSTRACT The morphogenesis of left-right (LR) asymmetry is a crucial phase of organogenesis. In the digestive tract, the development of anatomical asymmetry is first evident...

...Toby G. R. Andrews; Wolfram Pönisch; Ewa K. Paluch; Benjamin J. Steventon; Elia Benito-Gutierrez ABSTRACT Embryonic tissues are shaped by the dynamic behaviours of their constituent cells. To understand such cell behaviours and how they evolved, new approaches are needed to map out morphogenesis...

... cyclic physiological regeneration. Some of the multiple complex dermal components serve as a dermal niche for epidermal and melanocyte patterning morphogenesis, some differentiate to become nutrient providing pulp and some are reserved as quiescent dermal stem cells for the next feather cycle. Here, we...

... morphogenesis is regulated by the relative timing of epithelial versus mesenchymal cell convergence regulated by canonical Wnt signaling. Together, these studies reveal new aspects of Wnt/β-catenin signaling in tooth formation and in epithelial morphogenesis more broadly. References Andl , T...