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Keywords: Morphogenesis
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Journal Articles
Journal: Development
Development (2022) 149 (10): dev200236.
Published: 16 May 2022
... in epithelial morphogenesis defects, such as abnormal neural tube closure ( Balashova et al., 2017 ; Brown and Garcia-Garcia, 2018 ; Colas and Schoenwolf, 2001 ; Haigo et al., 2003 ; Itoh et al., 2014 ; Kowalczyk et al., 2021 ). The actomyosin system that drives apical constriction is a highly dynamic...
Includes: Supplementary data
Journal Articles
Journal: Development
Development dev.200359.
Published: 16 May 2022
... relentlessly building plant architecture and morphogenesis. Boundary domains display reduced growth and orchestrate development of adjacent tissues in a non-cell autonomous manner. How these two functions are achieved remains elusive despite the identification of several boundary-specific genes. Here, we show...
Journal Articles
Journal: Development
Development (2021) 148 (24): dev192914.
Published: 15 December 2021
... and shape the mammalian embryo. We detail how this can be complemented with precise measurements and manipulations of tissue biochemistry, mechanics and geometry across spatial and temporal scales to provide insights into the mechanochemical feedback loops governing embryo morphogenesis. Finally, we discuss...
Journal Articles
Journal: Development
Development (2021) 148 (23): dev199034.
Published: 3 December 2021
...Satoshi Yamashita; Boris Guirao; François Graner ABSTRACT Within developing tissues, cell proliferation, cell motility and other cell behaviors vary spatially, and this variability gives a complexity to the morphogenesis. Recently, novel formalisms have been developed to quantify tissue deformation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (19): dev199994.
Published: 4 October 2021
.... and Wittbrodt , J . ( 2009 ) . Ojoplano-mediated basal constriction is essential for optic cup morphogenesis . Development , 136 , 2165 - 2175 . 10.1242/dev.033563 Moreno-Mateos , M. A. , Vejnar , C. E. , Beaudoin , J.-D. , Fernandez , J. P. , Mis , E. K. , Khokha , M. K...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (17): dev199265.
Published: 6 September 2021
...Brent H. Wyatt; Nirav M. Amin; Kristen Bagley; Dustin J. Wcisel; Michael K. Dush; Jeffrey A. Yoder; Nanette M. Nascone-Yoder ABSTRACT The morphogenesis of left-right (LR) asymmetry is a crucial phase of organogenesis. In the digestive tract, the development of anatomical asymmetry is first evident...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (16): dev199430.
Published: 20 August 2021
...Toby G. R. Andrews; Wolfram Pönisch; Ewa K. Paluch; Benjamin J. Steventon; Elia Benito-Gutierrez ABSTRACT Embryonic tissues are shaped by the dynamic behaviours of their constituent cells. To understand such cell behaviours and how they evolved, new approaches are needed to map out morphogenesis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (18): dev198671.
Published: 3 August 2021
... contains signaling molecules to affect epidermal morphogenesis and pigment patterning ( Li et al., 2017 ; Lin et al., 2013 ). Formation of the pPP is an evolutionarily novel feature that allows for fine-tuning of signaling modules to build more complex feather architectures, with temporal changes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (14): dev199685.
Published: 22 July 2021
... morphogenesis is regulated by the relative timing of epithelial versus mesenchymal cell convergence regulated by canonical Wnt signaling. Together, these studies reveal new aspects of Wnt/β-catenin signaling in tooth formation and in epithelial morphogenesis more broadly. In skin, γ-catenin can compensate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (18): dev199459.
Published: 21 July 2021
...Susannah B. P. McLaren; Benjamin J. Steventon ABSTRACT How force generated by the morphogenesis of one tissue impacts the morphogenesis of other tissues to achieve an elongated embryo axis is not well understood. The notochord runs along the length of the somitic compartment and is flanked...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (14): dev199549.
Published: 21 July 2021
... of a developmental blueprint that defines the polarized organization of the apical cytoskeleton in hair cells, including stereocilia distribution and elongation. Here, we report a role for multiple PDZ domain (MPDZ) protein during apical hair cell morphogenesis in mouse. We show that MPDZ is enriched at the hair...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (14): dev199497.
Published: 12 July 2021
...David Oriola; Francesca M. Spagnoli ABSTRACT The second EMBO-EMBL Symposium ‘Synthetic Morphogenesis: From Gene Circuits to Tissue Architecture’ was held virtually in March 2021, with participants from all over the world joining from the comfort of their sofas to discuss synthetic morphogenesis...
Journal Articles
Journal: Development
Development (2021) 148 (13): dev198192.
Published: 6 July 2021
..., development of technologies for the reconstitution of a three-dimensional trachea from stem cells is urgently required. Recently, single-cell sequencing technologies and quantitative analyses from cell to tissue scale have been employed to decipher the cellular basis of tracheal morphogenesis. In this Review...
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2021) 148 (11): dev199232.
Published: 14 June 2021
... , T. and Lenne , P.-F. ( 2017 ). Viscoelastic dissipation stabilizes cell shape changes during tissue morphogenesis . Curr. Biol. 27 , 3132 - 3142.e4 . 10.1016/j.cub.2017.09.005 Coravos , J. S. and Martin , A. C. ( 2016 ). Apical sarcomere-like Actomyosin contracts...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (10): dev192054.
Published: 25 May 2021
... show that epithelial WNT5A is crucial for determining fourth ventricle (4V) ChP morphogenesis and size in mouse. Systemic Wnt5a knockout, or forced Wnt5a overexpression beginning at embryonic day 10.5, profoundly reduced ChP size and development. However, Wnt5a expression was enriched in Foxj1...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2021) 148 (18): dev199208.
Published: 18 May 2021
... obscures potential connections between morphogenesis and gonadal sex determination. To characterize the morphogenic processes implicated in regulating gonad shape and fate, we used whole-embryo tissue clearing and light sheet microscopy to assemble a time course of gonad development in native form...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (8): dev197343.
Published: 26 April 2021
... Morphogenesis Stress resilience Cytoprotection DNA damage Inflammation Oxidative stress Polyploidy Mitochondria Metabolic activity Drosophila Throughout their lifespan, body tissues are exposed to a variety of stressors, ranging from endogenous toxic byproducts (e.g. reactive oxygen species...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (8): dev195651.
Published: 23 April 2021
.... The loss of function of both genes ( Tbx2/3cDKO ) prevented inner ear morphogenesis at midgestation, resulting in indiscernible cochlear and vestibular structures at birth. Morphogenetic impairment occurred concomitantly with increased apoptosis in ventral and lateral regions of Tbx2/3cDKO otocysts around...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2021) 148 (4): dev195511.
Published: 26 February 2021
...Véronique Van De Bor; Vincent Loreau; Marilyne Malbouyres; Delphine Cerezo; Audrey Placenti; Florence Ruggiero; Stéphane Noselli ABSTRACT Basement membranes (BM) are extracellular matrices assembled into complex and highly organized networks essential for organ morphogenesis and function. However...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (24): dev191494.
Published: 23 December 2020
.... ( 2018 ). A dual role of the extracellular domain Drosophila Crumbs for morphogenesis of the embryonic neuroectoderm . Biol. Open   7 , bio031435 . 10.1242/bio.031435 Datta , A. , Bryant , D. M. and Mostov , K. E. ( 2011 ). Molecular regulation of lumen morphogenesis . Curr...
Includes: Supplementary data