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Keywords: Morphogen gradient
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Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2023) 150 (10): dev201702.
Published: 30 May 2023
...Jan A. Adelmann; Roman Vetter; Dagmar Iber ABSTRACT Tissue patterning during embryonic development is remarkably precise. Here, we numerically determine the impact of the cell diameter, gradient length and the morphogen source on the variability of morphogen gradients. We show that the positional...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (21): dev200940.
Published: 1 November 2022
... by measuring transcriptional kinetics at the endogenous short gastrulation locus, giving rise to distinct patterning consequences in the dorsal ectoderm of Drosophila embryos. Shadow enhancers MS2 live imaging Transcriptional kinetics Morphogen gradient Drosophila National Institutes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (7): dev192344.
Published: 6 April 2021
... scale invariance and adaptability to perturbations in gene expression and growth. In this Review, we document the diverse ways that BMP gradients are formed and refined, and we identify the core principles that they share to achieve reliable performance. Fig. 2. Morphogen gradient formation...
Journal Articles
Journal Articles
Journal: Development
Development (2019) 146 (21): dev181487.
Published: 12 November 2019
...Neta Rahimi; Inna Averbukh; Shari Carmon; Eyal D. Schejter; Naama Barkai; Ben-Zion Shilo ABSTRACT Establishment of morphogen gradients in the early Drosophila embryo is challenged by a diffusible extracellular milieu, and by rapid nuclear divisions that occur at the same time. To understand how...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (17): dev162792.
Published: 14 September 2018
... Lander , A. D. ( 2007 ). Morpheus unbound: reimagining the morphogen gradient . Cell   128 , 245 - 256 . 10.1016/j.cell.2007.01.004 Lee , J. L. and Streuli , C. H. ( 2014 ). Integrins and epithelial cell polarity . J. Cell Sci.   127 , 3217 - 3225 . 10.1242/jcs.146142...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (1): 124–135.
Published: 1 January 2014
... interrogations of the properties of morphogen gradients that instruct patterning. Recent studies of the Drosophila morphogen gradient Bicoid (Bcd), which is required for anterior-posterior (AP) patterning in the early embryo, have uncovered two distinct ways of scaling. Whereas between-species scaling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (15): 2730–2739.
Published: 1 August 2012
... no competing financial interests. 14 5 2012 © 2012. 2012 FGF Heparan sulfate Glycosaminoglycan Lacrimal gland Branching morphogenesis Morphogen gradient Mouse Glycosaminoglycans (GAGs) are the major constituents of the extracellular matrix that control the transport...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2011) 138 (13): 2741–2749.
Published: 1 July 2011
... (Bcd) morphogen gradient. Using embryos from lines artificially selected for large and small egg volume, we show that large embryos have higher nuclear Bcd concentrations in the anterior than small embryos. This anterior difference leads to scaling properties of the Bcd gradient profiles: in broad...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (11): 1923–1933.
Published: 1 June 2008
.... * Author for correspondence (e-mail: pai@mail.cgu.edu.tw ) 26 3 2008 © 2008. 2008 Gurken Egfr Cbl Morphogen gradient Endocytosis Drosophila Morphogens play pivotal roles during many important developmental stages to induce distinct cell fates by forming concentration...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (23): 5705–5716.
Published: 1 December 2003
..., Hungarian Academy of Sciences, Budapest H-1143, Hungary 13 8 2003 © 2003. 2003 BMP Morphogen gradient SMAD Dorsal-ventral patterning Drosophila Dorsal-ventral (DV) patterning of the Drosophila embryo is a paradigm for understanding the regulation of bone morphogenetic...
Journal Articles
Journal: Development
Development (2003) 130 (9): 1937–1947.
Published: 1 May 2003
.... and Niehrs, C. ( 2001 ). A morphogen gradient of Wnt/beta-catenin signalling regulates anteroposterior neural patterning in Xenopus. Development 128 , 4189 -4201. Kim, C. H., Oda, T., Itoh, M., Jiang, D., Artinger, K. B.,Chandrasekharappa, S. C., Driever, W. and Chitnis, A. B. ( 2000 ). Repressor...
Journal Articles
Journal: Development
Development (2003) 130 (8): 1515–1522.
Published: 15 April 2003
... protein and Dpp signal transduction is potentiated by Dally, a cell-surface heparan sulfate proteoglycan, during assembly of several adult tissues. However, the molecular mechanism by which the Dpp morphogen gradient is established and maintained is poorly understood. We show evidence that Dally regulates...
Journal Articles
Journal Articles
Journal: Development
Development (1999) 126 (23): 5309–5317.
Published: 1 December 1999
...: the role of the Xenopus homeobox gene goosecoid . Cell 67 , 1111 – 1120 . 10.1016/0092-8674(91)90288-A Dyson , S. and Gurdon , J. B. ( 1998 ). The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors . Cell 93 , 557 – 568...
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (1989) 107 (Supplement): 121–131.
Published: 1 April 1989
... and speculate about the possibility that retinoic acid influences the pattern of expression of homeobox genes. Copyright © 1989 by Company of Biologists 1989 limb morphogenesis molecular approach retinoic acid homeobox-containing genes retinoic acid receptor morphogen gradient retinoic-acid...