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Keywords: Midline facial clefts
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Journal Articles
Journal: Development
Development (2022) 149 (14): dev200533.
Published: 22 July 2022
.... Conditional inactivation of the Wnt secretion protein Wls in Pax3-expressing lineage cells disrupted frontonasal primordial patterning, cell survival and directional outgrowth, resulting in altered facial structures, including midfacial hypoplasia and midline facial clefts. Single-cell RNA sequencing revealed...
Includes: Supplementary data