Skip Nav Destination
1-1 of 1
Keywords: Midline facial cleftsClose
Ran Gu, Shuwen Zhang, Subbroto Kumar Saha, Yu Ji, Kurt Reynolds, Moira McMahon, Bo Sun, Mohammad Islam, Paul A. Trainor, YiPing Chen, Ying Xu, Yang Chai, Diana Burkart-Waco, Chengji J. Zhou
Development (2022) 149 (14): dev200533.
Published: 22 July 2022
.... Conditional inactivation of the Wnt secretion protein Wls in Pax3-expressing lineage cells disrupted frontonasal primordial patterning, cell survival and directional outgrowth, resulting in altered facial structures, including midfacial hypoplasia and midline facial clefts. Single-cell RNA sequencing revealed...
Includes: Supplementary data