... of Biologists Ltd 2019 Summary: Overexpression or knockdown of histones results in delayed or advanced cell cycle slowing and transcriptional activation at the mid-blastula transition, respectively, with differentially expressed genes associated with specific chromatin features. Chromatin...

... activation and DNA damage checkpoint acquisition at the mid-blastula transition . Cell Cycle   13 , 3828 - 3838 . 10.4161/15384101.2014.967066 Zhang , Y. , Vastenhouw , N. L. , Feng , J. , Fu , K. , Wang , C. , Ge , Y. , Pauli , A. , van Hummelen , P. , Schier...

...Junbo Liu; Jun Ma The Drosophila embryo at the mid-blastula transition (MBT) concurrently experiences a receding first wave of zygotic transcription and the surge of a massive second wave. It is not well understood how genes in the first wave become turned off transcriptionally and how...

...Xuemin Lu; Jennifer M. Li; Olivier Elemento; Saeed Tavazoie; Eric F. Wieschaus One of the most prominent features at the mid-blastula transition (MBT)observed in most embryos is a pause in cell cycle regulated by the nucleocytoplasmic (N/C) ratio. By using chromosome rearrangements to manipulate...

... a mid-blastula transition from maternal to embryonic control of development. In addition, we find that embryonic genes tend to be expressed transiently on a time scale consistent with developmental decisions being made with each cell cycle. Furthermore, overall rates of synthesis and degradation...