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Keywords: Microtubule growth
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Journal Articles

The microtubule end-binding proteins EB1 and Patronin modulate the spatiotemporal dynamics of myosin and pattern pulsed apical constriction

Anwesha Guru, Surat Saravanan, Deepanshu Sharma, Maithreyi Narasimha
Journal: Development
Development (2022) 149 (22): dev199759.
https://doi.org/10.1242/dev.199759
Published: 28 November 2022
... that microtubule growth from moving Patronin platforms governs the spatiotemporal dynamics of apicomedial myosin through the regulation of RhoGTPase signaling by transient EB1-RhoGEF2 interactions. We uncover the dynamic reorganization of a subset of short non-centrosomally nucleated apical microtubules...
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Includes: Supplementary data