... infertility was rescued successfully by in vitro microinsemination, the myr-Akt-Mer GS cells stopped differentiation at the round spermatid stage even after 8 months. At present,we can only speculate that myr-Akt-Mer protein was slightly activated by cross-reactivity with unknown endogenous steroid ligands...

... into postnatal seminiferous tubules of surrogate infertile mice. Furthermore, we obtained normal fertile offspring by microinsemination using spermatozoa or spermatids derived from PGCs harvested from fetuses as early as 8.5 days post coitum. Thus, fetal male germ cell development is remarkably flexible...