... Axial elongation Mechanics Young's modulus Viscoelasticity Biomechanics Extracellular matrix Microfilaments Xenopus Dorsal elongation and neural tube closure during early development are inherently mechanical events, yet little is known about the mechanical principles that drive...

... translocation are inseparable. We also learned that cortical granule translocation requires association with microfilaments but not microtubules. It is clear from endocytosis assays that microfilament motors are functional prior to meiosis, even though cortical granules do not use them. However, just after GVBD...

... shows that the mRNA is preferentially associated with a detergent-insoluble subcellular fraction. The use of cytoskeletal inhibitors suggests that (1) microtubules are involved in the translocation of the message to the vegetal hemisphere and (2) microfilaments are important for the anchoring...

...David P. Hill; Susan Strome ABSTRACT We are investigating the involvement of the microfilament cytoskeleton in the development of early Caenor-habditis elegans embryos. We previously reported that several cytoplasmic movements in the zygote require that the microfilament cytoskeleton remain intact...

... mRNA. Microtubule inhibitors such as nocodazole and colchicine inhibit the localization of Vgl mRNA in late stage in/early stage IV oocytes, but have no effect on Vgl mRNA once it is localized. The microfilament inhibitor cytochalasin B, however, has little effect on the translocation of Vgl mRNA...

... containing cytochalasin D (CCD) to disrupt the microfilament system. The blastomeres were analysed immediately for the distribution and state of organization of their microvilli, using three morphological techniques. The results indicate that the surface pole, characterized by microvilli containing CCD...

...Herwig O. Gutzeit; Erwin Huebner ABSTRACT The localization of F-actin (microfilaments) in the nurse cells of ovarian follicles has been studied in 12 different insect species by fluorescence microscopy after specifically staining F-actin with rhodamine-conjugated phalloidin. In the analysed species...

... not opposite to the contact point between cells. In contrast to surface polarity, the development of cytoplasmic polarity was suppressed by both microtubule- and microfilament-inhibiting drugs, which also reversed it rapidly. In polar 16-cell blastomeres surface polarity was influenced in a similar manner...

... of unscientific mysticism’ ( His, 1888 ). * Dedicated to Leslie J. Biberman. Copyright © 1985 by Company of Biologists 1985 cell adhesion computational embryology epithelia Eularian buckling finite element analysis microfilaments microtubules neurulation neural plate neural tube...

...Gillian Morriss-Kay; Fiona Tuckett ABSTRACT During the late stages of cranial neurulation in mammalian embryos, the neural epithelium becomes concave. A thick subapical band of microfilament bundles, attached to junctions which are both vertical and horizontal in orientation, can be seen by TEM...