... exhibits unexpected functional complexity as a regulator of epithelial morphogenesis, wound healing and immune responses. Drosophila Airway Chip-seq Epithelial maturation Grainy head Microarray Genes of the Grainy head (Grh) family encode conserved transcription factors (TFs...

..., formation of dorsal-ventral polarity, and endogenous initiation of the radicle. To reveal the transcriptional features associated with developmental events during rice early embryogenesis, we used microarray analysis coupled with laser microdissection to obtain both spatial and temporal transcription...

... is disorganized in the Olig2-KO dorsal thalamus, and initial elongation of TCAs is retarded in the Olig2-KO forebrain. Microarray analysis demonstrated upregulation of several axon guidance molecules, including Epha3 and Epha5 , in the Olig2-KO basal forebrain. In situ hybridization showed that the prethalamus...

... Somitogenesis Segmentation Evolution Cyclic genes Segmentation clock Microarray Chicken Zebrafish Mouse Notch Wnt FGF The periodic organization of the vertebrate body, which is most visible in the vertebrae, is established during embryogenesis. In vertebrates, a complex signaling pulse from...

... large-scale in situ hybridisation screens (wholemount and section) and microarray gene expression data of microdissected, laser-captured and FACS-sorted components of the developing mouse genitourinary (GU) system. These expression data are annotated using a high-resolution anatomy ontology specific...

... in the endomesoderm. Both microarray and QPCR data show that, in embryos consisting mostly of the APD, Six3 suppresses expression of the Wnt genes, and nodal, lefty and chordin ( Table 3 ; Fig. 8 ). However, in normal embryos (glycerol-injected), Six3 repression of these genes cannot be detected( Table 3 ; Fig...

.... * Author for correspondence (e-mail: [email protected] ) 12 5 2008 © 2008. 2008 E2F transcription factor Mammary gland Microarray Mouse The vast majority of mammary gland development occurs after birth, when the epithelial network undergoes a rapid expansion to fill...

... networks to regulate the balance between hair follicle and epidermal cell fates. * Author for correspondence (e-mail: [email protected] ) 31 10 2006 © 2007. 2007 Gata3 Hair follicle Epidermis Laser capture microscopy Microarray Mouse The hair follicle (HF...

... cellular behavior. We have quantitatively identified hundreds of Hox downstream genes in Drosophila by microarray analysis, and validated many of them by in situ hybridizations on loss- and gain-of-function mutants. One important finding is that Hox proteins, despite their similar DNA-binding properties...

... ontology information for microarray analysis. Nucleic Acids Res . 31 , 3483 -3486. Zhu, L., Tran, T., Rukstalis, J. M., Sun, P., Damsz, B. and Konieczny, S. F. ( 2004 ). Inhibition of Mist1 homodimer formation induces pancreatic acinar-to-ductal metaplasia. Mol. Cell. Biol . 24 , 2673 -2681...

... a combination of microarray analysis and loss-of-function experiments to examine the global regulatory network controlling Xenopus endoderm formation. We identified over 300 transcripts enriched in the gastrula endoderm, including most of the known endoderm regulators and over a hundred uncharacterized genes...

... of expression of retinal markers. Fate mapping analysis using a multifunctional Chx10 BAC reporter mouse revealed this process to be direct transdifferentiation of retinal cells into pigmented cells. Microarray and in situ hybridization analyses revealed a complex program underlying the transdifferentiation...

...S. Raisa Eng; Jason Lanier; Natalia Fedtsova; Eric E. Turner Mice lacking the POU-domain transcription factor Brn3a exhibit marked defects in sensory axon growth and abnormal sensory apoptosis. We have determined the regulatory targets of Brn3a in the developing trigeminal ganglion using microarray...

...Michelle N. Arbeitman; Alice A. Fleming; Mark L. Siegal; Brian H. Null; Bruce S. Baker In virtually all animals, males and females are morphologically,physiologically and behaviorally distinct. Using cDNA microarrays representing one-third of Drosophila genes to identify genes expressed sex...

... equally to this work and are listed alphabetically † Present address: Division of Developmental Biology, Cincinnati Children's Research Foundation, Cincinnati, OH 45229-3039, USA 30 9 2003 © 2004. 2004 Myt1 endoderm Pancreas Endocrine Islets Microarray...

.... * Author for correspondence (e-mail: [email protected] ) 10 9 2003 © The Company of Biologists Limited 2003 2003 Microarray Anteroposterior axis Gastrulation Signalling pathways Tdgf1 Nanog Tissue and organ development of vertebrates is tightly regulated by signalling...

...John Wang; Stuart K. Kim The dauer is a developmental stage in C. elegans that exhibits increased longevity, stress resistance, nictation and altered metabolism compared with normal worms. We have used DNA microarrays to profile gene expression differences during the transition from the dauer state...

... transcription Microarray C. elegans Molecular and genetic analysis has elucidated the mechanistic basis of embryogenesis. In addition to identifying and characterizing many key molecules and the processes they control, these analyses have also provided broad insight into embryogenesis, suggesting...

... (distal). We applied DNA microarray analysis to discover genes with potential roles in the development of these regions. We identified a set of 94 transcripts enriched (two fold or greater) in the body wall and 56 transcripts enriched in the wing/hinge region. Transcripts that are known to have highly...

...2002. 2002 Microarray Fibroblast growth factor receptors FGF3 FGF7 FGF10 BMP4 BMP7 Submandibular gland Organ culture SU5402 Mouse The embryonic mouse submandibular salivary gland (SMG) is a classic developmental model system used to study epithelialmesenchymal interactions...