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Keywords: MicroRNA
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Journal Articles
Journal: Development
Development (2020) 147 (24): dev192948.
Published: 24 December 2020
... defects. Here, we propose the first developmental stage-specific network approach by integrating two crucial regulators, transcription factors (TFs) and microRNAs (miRNAs), to study their co-regulation during craniofacial development. Specifically, we used TFs, miRNAs and non-TF genes to form feed-forward...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2020) 147 (8): dev183723.
Published: 12 April 2020
... protein to enable accumulation of yolk protein in oocytes during vitellogenesis. MicroRNA Transgene Oogenesis Vitellogenin receptor Bombyx mori An inherently high reproductive capacity (rate) is an important strategy of insects, which enhances their chances of survival in nature...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (21): dev183111.
Published: 06 November 2019
...Orkan Ilbay; Victor Ambros ABSTRACT MicroRNAs target complementary mRNAs for degradation or translational repression, reducing or preventing protein synthesis. In Caenorhabditis elegans , the transcription factor HBL-1 (Hunchback-like 1) promotes early larval (L2)-stage cell fates, and the let-7...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2019) 146 (17): dev177097.
Published: 02 September 2019
...Daria Bloch; Malikarjuna Rao Puli; Assaf Mosquna; Shaul Yalovsky ABSTRACT Patterning of the root xylem into protoxylem (PX) and metaxylem is regulated by auxin-cytokinin signaling and microRNA miR165a/166b -mediated suppression of genes encoding Class III HOMEODOMAIN LEU-ZIPPER (HD-ZIPIII) proteins...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (7): dev167056.
Published: 04 April 2019
... of the germ cell fate. Germ cell Germ plasm microRNA Transcriptional repression Maternal-to-zygotic transition In many animals, including Drosophila , Xenopus and zebrafish, germ cell specification and maintenance depends on maternally provided RNAs and proteins located in the germ plasm...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2019) 146 (5): dev172932.
Published: 01 March 2019
...Delfina A. Ré; Patricia L. M. Lang; Cristian Yones; Agustin L. Arce; Georgina Stegmayer; Diego Milone; Pablo A. Manavella ABSTRACT Plants use molecular mechanisms to sense temperatures, trigger quick adaptive responses and thereby cope with environmental changes. MicroRNAs (miRNAs) are key...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2018) 145 (24): dev170670.
Published: 17 December 2018
... been extensively studied, little is known about its regulation at the post-transcriptional level. Using the migratory locust Locusta migratoria as a model system, we report here that the microRNAs let-7 and miR-278 bound to the Kr-h1 coding sequence and downregulated its expression. Application of let...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (20): dev161133.
Published: 16 October 2018
...Richard Kaschula; Sofia Pinho; Claudio R. Alonso ABSTRACT Disruptions of normal Hox gene expression can lead to severe morphological defects, revealing a link between the regulation of Hox expression and pattern formation. Here, we explore these links, focusing on the impact of microRNA regulation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (15): dev162594.
Published: 02 August 2018
... microRNAs (miRNAs) play crucial roles in skeletal development and homeostasis by suppressing target gene expression ( Mirzamohammadi et al., 2014 ; Papaioannou et al., 2014 ). We have shown that miRNAs play important roles in chondrocyte proliferation, differentiation and survival, both in the growth plate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (13): dev153817.
Published: 06 July 2018
...Moritz Sander; Teresa Eichenlaub; Héctor Herranz ABSTRACT Tissue growth has to be carefully controlled to generate well-functioning organs. MicroRNAs are small non-coding RNAs that modulate the activity of target genes and play a pivotal role in animal development. Understanding the functions...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (10): dev151415.
Published: 14 May 2018
... to the repellent Sema3a is regulated by translational control of Neuropilin 1 expression in a microRNA (miRNA)-dependent manner ( Baudet et al., 2012 ). A role for miRNAs in axonal connectivity in the visual system was suggested previously by the perturbation of the miRNA processing pathway component Dicer1...
Journal Articles
Journal: Development
Development (2018) 145 (7): dev159053.
Published: 09 April 2018
... , D. , Dai , Q. , Sun , K. , Saj , A. , Chou , Y.-T. , Raleigh , D. R. , Kim , K. , Ni , J.-Q. , Duan , H. , et al. ( 2012 ). A genome-wide transgenic resource for conditional expression of Drosophila microRNAs . Development   139 , 2821 - 2831 . 10.1242/dev...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2017) 144 (20): 3731–3743.
Published: 15 October 2017
...Alireza Paikari; Cassandra D. Belair; Daniel Saw; Robert Blelloch The vertebrate-specific ESCC microRNA family arises from two genetic loci in mammals: miR-290/miR-371 and miR-302. The miR-302 locus is found broadly among vertebrates, whereas the miR-290/miR-371 locus is unique to eutheria...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2017) 144 (11): 1959–1965.
Published: 01 June 2017
.../s10722-014-0213-3 Aukerman , M. J. and Sakai , H. ( 2003 ). Regulation of flowering time and floral organ identity by a microRNA and its APETALA2-like target genes . Plant Cell   15 , 2730 - 2741 . 10.1105/tpc.016238 Boden , S. A. , Cavanagh , C. , Cullis , B. R...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (10): 1787–1797.
Published: 15 May 2017
...Elijah J. Spina; Elmer Guzman; Hongjun Zhou; Kenneth S. Kosik; William C. Smith Here we present a parallel study of mRNA and microRNA expression during oral siphon (OS) regeneration in Ciona robusta , and the derived network of their interactions. In the process of identifying 248 mRNAs and 15...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (23): 4474–4485.
Published: 01 December 2016
.../user-licence-1-1/ Summary: Elav – the canonical Drosophila marker for post-mitotic neurons – has a previously unrecognized component of ubiquitous expression that is suppressed by the microRNA pathway, including by miR-279/996. In the course of examining clonal phenotypes of miRNA...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (22): 4137–4148.
Published: 15 November 2016
...Amir Mizbani; Edlira Luca; Elisabeth J. Rushing; Jan Krützfeldt MicroRNAs (miRNAs) are important regulators of skeletal muscle regeneration, but the underlying mechanisms are still incompletely understood. Here, comparative miRNA sequencing analysis of myogenic progenitor cells (MPs) and non...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2016) 143 (17): 3061–3073.
Published: 01 September 2016
...Stephanie Hilz; Andrew J. Modzelewski; Paula E. Cohen; Andrew Grimson MicroRNAs and siRNAs, both of which are AGO-bound small RNAs, are essential for mammalian spermatogenesis. Although their precise germline roles remain largely uncharacterized, recent discoveries suggest that they function...
Journal Articles
Journal: Development
Development (2016) 143 (13): 2292–2304.
Published: 01 July 2016
... the Shh signaling response, causing cell cycle exit and differentiation. We tested this hypothesis using genetic and pharmacological manipulation, gene expression analysis and time-lapse imaging of zebrafish embryos. Blocking the function of miR-219, a microRNA that downregulates apical Par polarity...
Journal Articles
Journal: Development
Development (2015) 142 (21): 3713–3720.
Published: 01 November 2015
...Ruifen Weng; Stephen M. Cohen Post-transcriptional regulation of stem cell self-renewal by microRNAs is emerging as an important mechanism controlling tissue homeostasis. Here, we provide evidence that bantam microRNA controls neuroblast number and proliferation in the Drosophila central brain...
Includes: Supplementary data