... their differentiation into kidney tubular tissue. † Author for correspondence (e-mail: tschulth@bidmc.harvard.edu ) * These authors contributed equally to this work 15 5 2006 © 2006. 2006 Kidney Metanephros Mesonephros Chick embryo Mouse Osr1 Odd1 Vertebrate kidney tissue...

... of a failure of nephric duct formation, precluding studies of the role of Lim1 at later stages of kidney development. Here, we show that Lim1 functions in distinct tissue compartments of the developing metanephros for both proper development of the ureteric buds and the patterning of renal vesicles for nephron...

... by failure of mesenchyme to epithelium signaling. In situ hybridizations with Wnt7b , a marker of the metanephric kidney, show that the branching defect was not simply the result of homeotic transformation of metanephros to mesonephros. Absent Bf2 and Gdnf expression in the midventral mesenchyme, findings...

... Kidney development Metanephros The development of vertebrate organs requires intricate cell and tissue interactions to assure the concerted program of cell growth, differentiation and morphogenesis. The mammalian kidney, mainly of mouse and rat, has long been studied as a model system to reveal...

... 1996 Wnt kidney development metanephros proteoglycans Danforth’s short-tail mouse The development of vertebrate organs requires intricate cell-cell communications to assure the concerted program of cell growth, differentiation and morphogenesis. Renal development is characterized...

... traced the lineage of distinct cell types back to a common multipotent progenitor. metanephros lineage analysis stem cells renal development © 1992 by Company of Biologists 1992 26 11 1991 † Permanent address: National Institute of Cardiovascular Research, Osaka, Japan...