... and developmental time scales, keeping the whole organism in view during development is particularly challenging for mammals. Beyond elucidating the molecular mechanisms that explain how nutritional and metabolic signals control genetic and developmental events, understanding the underlying logic...

... affect multiple aspects of animal development. In this Review, we discuss how metabolism is mechanistically linked to cellular and developmental programs through both its bioenergetic and metabolic signaling functions. We highlight how metabolism is regulated across various spatial and temporal scales...