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Keywords: Mesoderm migrationClose
Development (2009) 136 (14): 2393–2402.
Published: 15 July 2009
... activation in migrating mesoderm cells. The results support the model that Pyr acts as an instructive cue for mesoderm migration during gastrulation. Consistent with this function, mutations in pyr affect the normal segmental number of cardioblasts. Furthermore, Pyr is essential for the specification of even...
Includes: Supplementary data
Andreas van Impel, Sabine Schumacher, Margarethe Draga, Hans-Martin Herz, Jörg Großhans, H. Arno J. Müller
Development (2009) 136 (5): 813–822.
Published: 1 March 2009
... during mesoderm migration. Genetic and biochemical interactions indicate that during mesoderm migration, Pbl functions by activating a Rac-dependent pathway. Furthermore,gain-of-function and rescue experiments suggest an important regulatory role of the C-terminal tail of Pbl for the selective activation...
Includes: Multimedia, Supplementary data