... of specialized lymphatic endothelial cells (LECs) and their subsequent assembly in primary lymphatic vessels. Although lymphatic cells are in continuous contact with mesenchymal cells during development and in adult tissues, the role of mesenchymal cells in lymphatic vasculature development remains poorly...

.... Deficiency of epithelial Erk1/2 results in defects in secretory cell differentiation as well as impaired mesenchymal cell proliferation and maturation. Deletion of Erk1/2 strongly activated Wnt signaling through both cell-autonomous and non-autonomous mechanisms. In epithelial cells, Erk1/2 depletion...

... cell miRNA During lung organogenesis, mesenchymal cells undergo active proliferation to support the continuous growth of the organ. Simultaneously, many cells are actively differentiating into the specific cell types that will populate the adult lung - such as parabronchial and vascular...