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Keywords: Mesencephalon
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Journal Articles
Journal: Development
Development (2010) 137 (11): 1897–1906.
Published: 1 June 2010
... cells in the spinal cord were correctly specified, but could not properly mature. By contrast, in the developing mesencephalon, loss of Nato3 did not affect FP differentiation, but led to loss of neurogenic activity in the medial subpopulation of mesFP cells by suppressing proneural gene expression...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (15): 2783–2793.
Published: 1 August 2007
...Tomoya Nakatani; Yasuko Minaki; Minoru Kumai; Yuichi Ono The mechanism underlying the determination of neurotransmitter phenotype in the developing mesencephalon, particularly GABAergic versus glutamatergic fate, remains largely unknown. Here, we show in mice that the basic helix-loop-helix...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (14): 3209–3216.
Published: 15 July 2005
... gene ( Crossley et al.,1996 ; Lee et al.,1997 ; Reifers et al.,1998 ; Martinez et al.,1999 ), appears to respect the lineage boundary at its anterior end. In this study we have shown that the mesencephalon and metencephalon of the zebrafish embryo are separated by a lineage restriction...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (14): 3163–3173.
Published: 15 July 2005
... caudally. At 24 hpf, lmx1b.1 and lmx1b.2 are expressed at the caudal limit of the mesencephalon that abuts the isthmic constriction in a pattern similar to the wnt1 expression domain( Fig. 3D-F ). All three genes are also expressed in the dorsal midline of the mesencephalon and metencephalon...
Journal Articles
Journal: Development
Development (2005) 132 (8): 1785–1793.
Published: 15 April 2005
... 1 2 2005 ©2005. 2005 Sax1 Emx2 Six3 Pax6 Mesencephalon Tegmentum Medial longitudinal fascicle Posterior commissure Early axon scaffold A characteristic feature of all vertebrates is the formation of a conserved set of longitudinal and commissural axon tracts...
Journal Articles
Journal: Development
Development (2003) 130 (12): 2633–2644.
Published: 15 June 2003
...Candace L. Chi; Salvador Martinez; Wolfgang Wurst; Gail R. Martin Numerous studies have demonstrated that the midbrain and cerebellum develop from a region of the early neural tube comprising two distinct territories known as the mesencephalon (mes) and rostral metencephalon (met; rhombomere 1...
Journal Articles
Journal: Development
Development (2001) 128 (13): 2461–2469.
Published: 1 July 2001
...Tatsuya Sato; Isato Araki; Harukazu Nakamura The mes/metencephalic boundary (isthmus) has an organizing activity for mesencephalon and metencephalon. The candidate signaling molecule is Fgf8 whose mRNA is localized in the region where the cerebellum differentiates. Responding to this signal...
Journal Articles
Journal: Development
Development (2000) 127 (9): 1857–1867.
Published: 1 May 2000
...Kirk A. Adams; Jennifer M. Maida; Jeffrey A. Golden; Robert D. Riddle ABSTRACT Cells in the caudal mesencephalon and rostral metencephalon become organized by signals emanating from the isthmus organizer (IsO). The IsO is associated with the isthmus, a morphological constriction of the neural tube...
Journal Articles
Journal: Development
Development (1999) 126 (22): 5127–5135.
Published: 15 November 1999
...Isato Araki; Harukazu Nakamura Regionalization of a simple neural tube is a fundamental event during the development of central nervous system. To analyze in vivo the molecular mechanisms underlying the development of mesencephalon, we ectopically expressed Engrailed, which is expressed...
Journal Articles
Journal: Development
Development (1999) 126 (14): 3191–3203.
Published: 15 July 1999
... constriction ( Fig. 1C ). The resulting chimeric embryos ( n =7, see Table 1 ) were integrated within rh1. In midsagittal sections ( Fig. 3A ), its rostral border contacted the host mesencephalon and its caudal border the host choroid tissue ( Fig. 3A,D ), two Otx2 -positive domains. In more lateral...
Journal Articles
Journal: Development
Development (1997) 124 (5): 959–969.
Published: 1 March 1997
...Scott M. K. Lee; Paul S. Danielian; Bernd Fritzsch; Andrew P. McMahon ABSTRACT The developing vertebrate mesencephalon shows a rostrocaudal gradient in the expression of a number of molecular markers and in the cytoarchitectonic differentiation of the tectum, where cells cease proliferating...
Journal Articles