...Erine H. Budi; Larissa B. Patterson; David M. Parichy Vertebrate pigment cells are derived from neural crest cells and are a useful system for studying neural crest-derived traits during post-embryonic development. In zebrafish, neural crest-derived melanophores differentiate during embryogenesis...

..., the zebrafish D. rerio , is a model organism for biomedical research. Previous studies have shown that in zebrafish, stripes form by migration and differentiation of distinct populations of melanophores:early metamorphic (EM) melanophores arise widely dispersed and then migrate into stripes, whereas late...

... crest derivatives. Embryos mutant for choker manifest a unique pigment pattern phenotype that combines a loss of lateral stripe melanophores with an ectopic melanophore `collar' at the head-trunk border. We find that defects in neural crest migration are largely restricted to the lateral migration...

... expressed by Danio fishes. These patterns result from several classes of pigment cells including black melanophores and yellow xanthophores, which differentiate during metamorphosis from latent stem cells of presumptive neural crest origin. In the zebrafish D. rerio ,alternating light and dark horizontal...

...Florian Maderspacher; Christiane Nüsslein-Volhard Colour patterns are a prominent feature of many animals and are of high evolutionary relevance. In zebrafish, the adult pigment pattern comprises alternating stripes of two pigment cell types, melanophores and xanthophores. How the stripes...

... , alternating horizontal stripes of black melanophores and yellow xanthophores are a prominent feature of the adult pigment pattern. In fms mutant zebrafish, however, xanthophores fail to develop and melanophore stripes are severely disrupted. fms encodes a type III receptor tyrosine kinase expressed...

... fertilisation. We provide evidence that melanophore defects in colourless mutants can be largely explained by disruption of nacre/mitf expression. We propose that all defects of affected crest derivatives are consistent with a primary role for colourless/sox10 in specification of non-ectomesenchymal crest...

...@bath.ac.uk ) 19 11 1999 12 01 2000 © 2000 by Company of Biologists 2000 Zebrafish Neural crest Cell fate Melanophore Xanthophore Iridophore Neuron Glia The process whereby precursor cells become specified to generate progeny with distinct fates is fundamental...

... of multiple chromatophores (Classes VI.D-H). Their further characterisation should then reveal aspects of the genetic control of organelle synthesis. Melanophore morphology mutants (Classes VII.A-C) may be analogous to mouse mutations such as d , and will also be inter-esting in terms of the genetic control...

... ), are induced to differentiate in these heparin-injected embryos. I stained frozen sections of controls and larvae that had been injected with 30 nl polysaccharide with Mab Mel, which is specific for neural-crest-derived melanophores and retinal pigment cells. The former was easily distinguished from...

...S. K. Frost; L. G. Epp; S. J. Robinson ABSTRACT The axanthic mutant in the Mexican axolotl ( Ambystoma mexicanum ) was analysed with respect to the differentiation of pigment cells. Transmission electron micrographs revealed the presence of melanophores and cells that are described as unpigmented...

... reach a mature state earlier than they do in wild-type axolotl skin. This morphology is conserved throughout development in albino animals whereas it is gradually lost in the wild type. Unpigmented melanophores from albino axolotls are illustrated for the first time, and in larval albino axolotls...

...T. Fukuzawa; H. Ide ABSTRACT It is still unknown why dermal melanophores disappear during larval development, and why no or very few epidermal melanophores appear during and after metamorphosis, in Xenopus laevis showing periodic albinism ( a p ). To elucidate these points, we investigated (1...