... is identified as an immediate downstream target of endothelin and is part of a positive-feedback mechanism for endothelin induction in the neural crest. Endothelin MEF2C Craniofacial development Melanocytes Neural crest Transcription Mouse The Endothelin signaling pathway triggers several...

..., conditional β-catenin inactivation in premigratory neural crest cells abolishes both sensory neuron and melanocyte formation. Intriguingly, the generation of melanocytes is also prevented by activation of β-catenin in the premigratory neural crest, which promotes sensory neurogenesis at the expense of other...

...Hitomi Aoki; Yasuhiro Yamada; Akira Hara; Takahiro Kunisada Unlike the thoroughly investigated melanocyte population in the hair follicle of the epidermis, the growth and differentiation requirements of the melanocytes in the eye, harderian gland and inner ear - the so-called non-cutaneous...

...: Department of Neurology, Weill Medical College of Cornell University, New York, NY 10021, USA 1 8 2006 © 2006. 2006 Neural crest Induction Sox9 Sox10 Craniofacial Melanocytes Xenopus Members of the Sox family of transcription factors are important regulators of multiple...

..., because of the difficulty of identifying individual stem cells and their surrounding components in situ, the exact mechanisms underlying SC regulation by the niche remain elusive. To overcome this difficulty, we employed melanocyte stem cells (MSCs), which allow the identification of individual SCs...

...Carol A. Erickson; Tina L. Goins ABSTRACT Neural crest cells are conventionally believed to migrate arbitrarily into various pathways and to differentiate according to the environmental cues that they encounter. We present data consistent with the notion that melanocytes are directed, by virtue...

...Susan D. Porter; Cathy J. Meyer ABSTRACT We have assessed the importance of a melanocyte-specific DNase I hypersensitive site and matrix attachment region situated 15 kb upstream of the mouse tyrosinase gene by analysis in transgenic mice. Transgenes containing all, part, or none of this region...

.... It was concluded that cells recovered from the stage X embryo can subsequently contribute to melanocytes derived from the neural crest, to erythrocytes and to germ cells. This technique of blastodermal cell transfer should be useful in developmental studies and may facilitate the production of transgenic poultry...

... the neural crest. Intermediate cells are melanocyte-like cells, presumably derived from the neural crest, and are scattered between the marginal and basal cell layers. The marginal cells form extensive interdigitations with the basal and intermediate cells in the normal adult stria. The stria also contains...