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Keywords: Meis
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Journal Articles
Journal: Development
Development (2019) 146 (16): dev174706.
Published: 15 August 2019
...Dorothea Schulte; Dirk Geerts ABSTRACT MEIS transcription factors are key regulators of embryonic development and cancer. Research on MEIS genes in the embryo and in stem cell systems has revealed novel and surprising mechanisms by which these proteins control gene expression. This Primer...
Journal Articles
Journal: Development
Development (2016) 143 (2): 276–285.
Published: 15 January 2016
... Meis genes . Development   127 , 3961 - 3970 . Mercader , N. , Selleri , L. , Criado , L. M. , Pallares , P. , Parras , C. , Cleary , M. L. and Torres , M. ( 2009 ). Ectopic Meis1 expression in the mouse limb bud alters P-D patterning in a Pbx1-independent manner...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (7): 1534–1543.
Published: 01 April 2014
... . Mercader N. , Leonardo E. , Piedra M. E. , Martínez-A C. , Ros M. A. , Torres M. ( 2000 ). Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes . Development 127 , 3961 – 3970 . Mercader N. , Tanaka E...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (3): 513–518.
Published: 01 February 2013
... distal transformation. They also have nuclear MEIS, which can act as an upper arm identity regulator, only upon upper arm amputation. By contrast, myogenic cells do not obey the rule of distal transformation and display nuclear MEIS upon amputation at any proximo-distal level. These results indicate that...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (5): 805–811.
Published: 01 March 2008
... RPCs throughout the period of neurogenesis in the retina, whereas Meis2 is specific for RPCs prior to the onset of retinal differentiation. Transfection of Meis-inactivating constructs impaired RPC proliferation and led to microphthalmia. RNA-interference-mediated knock-down of expression indicated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (3): 613–627.
Published: 01 February 2004
... with either Prep and Meis. In fact, in Drosophila , Exd is destabilized and degraded in the absence of Hth( Kurant et al., 2001 ), and lack of Prep1 in mice coincides with a strong, widespread reduction of the levels of all Pbx proteins (E.F. and F.B., unpublished). Moreover,overexpression of Prep1 in...
Journal Articles
Journal: Development
Development (2003) 130 (4): 741–751.
Published: 15 February 2003
... proteins to a larger family of non-Hox homeodomain proteins. * Author for correspondence (e-mail: Jim.Jaynes@mail.tju.edu ) 7 11 2002 © 2003. 2003 Drosophila Embryogenesis Homeodomain Transcription Repressor Cofactor Pbx Meis The engrailed ( en ) gene is a...
Journal Articles
Journal: Development
Development (2002) 129 (19): 4371–4386.
Published: 01 October 2002
... cooperative DNA binding with Pbx-Meis/Prep1. Nucleic Acids Res . 27 , 3752 -3761. Kohlhase, J., Wischermann, A., Reichenbach, H., Froster, U. and Engel, W. ( 1998 ). Mutations in the SALL1 putative transcription factor gene cause Townes-Brocks syndrome. Nat. Genet . 18 , 81 -83. Kojima, T...
Journal Articles
Journal: Development
Development (2002) 129 (3): 585–595.
Published: 01 February 2002
...Seong-Kyu Choe; Nikolaos Vlachakis; Charles G. Sagerström Meis homeodomain proteins function as Hox-cofactors by binding Pbx and Hox proteins to form multimeric complexes that control transcription of genes involved in development and differentiation. It is not known what role Meis proteins play...
Journal Articles
Journal: Development
Development (2001) 128 (21): 4139–4151.
Published: 01 November 2001
..., and probably function by revealing the intrinsic specificity of Hox proteins. Vertebrate orthologs of Exd and Hth, known as Pbx and Meis (named for a myeloid ecotropic leukemia virus integration site), respectively, are encoded by multigene families and are present in multimeric complexes together...
Journal Articles
Journal: Development
Development (2001) 128 (18): 3405–3413.
Published: 15 September 2001
... HTH. The HTH antimorph described in this work presents a new means by which the transcriptional activity of the endogenous HTH protein can be blocked in an inducible fashion in any desired cells or tissues without interfering with nuclear localization of EXD. © 2001. 2001 Meis Transcription...
Journal Articles
Journal: Development
Development (2001) 128 (18): 3595–3607.
Published: 15 September 2001
... -5228. Chan, S.-K., Ryoo, H.-D., Gould, A., Krumlauf, R. and Mann, R. ( 1997 ). Switching the in vivo specificity of a minimal HOX -responsive element. Development 124 , 2007 -2014. Chang, C. P., Jacobs, Y., Nakamura, T., Jenkins, N. A., Copeland, N. G. and Cleary, M. L. ( 1997 ). Meis...