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Keywords: Meis
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Journal Articles
Journal: Development
Development (2019) 146 (16): dev174706.
Published: 15 August 2019
...Dorothea Schulte; Dirk Geerts ABSTRACT MEIS transcription factors are key regulators of embryonic development and cancer. Research on MEIS genes in the embryo and in stem cell systems has revealed novel and surprising mechanisms by which these proteins control gene expression. This Primer...
Journal Articles
Journal: Development
Development (2016) 143 (2): 276–285.
Published: 15 January 2016
... to regulate MEIS expression. Meis Mouse limb development Polycomb Proximal-distal specification RING1 Polycomb group (PcG) genes were originally identified as encoding regulators of Hox genes in Drosophila and are evolutionarily conserved among metazoans (reviewed by Lanzuolo and Orlando...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (7): 1534–1543.
Published: 1 April 2014
...-synthesis enzymes Raldh2 or Rdh10 ( Cunningham et al., 2013 ; Zhao et al., 2009b ). These studies show that hindlimb (but not forelimb) patterning can proceed normally (including Meis expression) in situations in which RA signaling is not detected by a genetically encoded RA reporter ( RARE-lacZ...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2008) 135 (5): 805–811.
Published: 1 March 2008
... RPCs throughout the period of neurogenesis in the retina, whereas Meis2 is specific for RPCs prior to the onset of retinal differentiation. Transfection of Meis-inactivating constructs impaired RPC proliferation and led to microphthalmia. RNA-interference-mediated knock-down of expression indicated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (3): 613–627.
Published: 1 February 2004
... chondrogenesis and, acting as a member of Meinox-Pbc-Hox trimers, it plays an essential role in hindbrain development. * Author for correspondence (e-mail: francesco.argenton@unipd.it ) 27 10 2003 © 2004. 2004 Vertebrate Zebrafish Hox Pbx Meis Prep Rhombomere Segmentation...
Journal Articles
Journal: Development
Development (2003) 130 (4): 741–751.
Published: 15 February 2003
... to a larger family of non-Hox homeodomain proteins. * Author for correspondence (e-mail: Jim.Jaynes@mail.tju.edu ) 7 11 2002 © 2003. 2003 Drosophila Embryogenesis Homeodomain Transcription Repressor Cofactor Pbx Meis The engrailed ( en ) gene is a homeobox...
Journal Articles
Journal: Development
Development (2002) 129 (19): 4371–4386.
Published: 1 October 2002
... mediates cooperative DNA binding with Pbx-Meis/Prep1. Nucleic Acids Res . 27 , 3752 -3761. Kohlhase, J., Wischermann, A., Reichenbach, H., Froster, U. and Engel, W. ( 1998 ). Mutations in the SALL1 putative transcription factor gene cause Townes-Brocks syndrome. Nat. Genet . 18 , 81 -83...
Journal Articles
Journal: Development
Development (2002) 129 (3): 585–595.
Published: 1 February 2002
...Seong-Kyu Choe; Nikolaos Vlachakis; Charles G. Sagerström Meis homeodomain proteins function as Hox-cofactors by binding Pbx and Hox proteins to form multimeric complexes that control transcription of genes involved in development and differentiation. It is not known what role Meis proteins play...
Journal Articles
Journal: Development
Development (2001) 128 (21): 4139–4151.
Published: 1 November 2001
..., and probably function by revealing the intrinsic specificity of Hox proteins. Vertebrate orthologs of Exd and Hth, known as Pbx and Meis (named for a myeloid ecotropic leukemia virus integration site), respectively, are encoded by multigene families and are present in multimeric complexes together...
Journal Articles
Journal: Development
Development (2001) 128 (18): 3405–3413.
Published: 15 September 2001
... homologues. HTH belongs to the Meis family of proteins. These proteins contain both a homeodomain and a Meis-homology domain. The Meis-homology domain is required for their interaction with PBC proteins and the nuclear localization of the latter ( Knoepfler et al., 1997 ; Berthelsen et al., 1998 ; Ryoo et...
Journal Articles
Journal Articles
Journal: Development
Development (1999) 126 (22): 5137–5148.
Published: 15 November 1999
... homothorax MEIS Hox extradenticle pbx Drosophila melanogaster In developmental biology, the term selector gene has been used to describe genes that are able to trigger an entire developmental pathway ( Garcia-Bellido, 1975 ). For example, in Drosophila melanogaster the genes eyeless...
Journal Articles
Journal: Development
Development (1998) 125 (19): 3821–3830.
Published: 1 October 1998
...Muna Abu-Shaar; Richard S. Mann ABSTRACT homothorax ( hth ) is a Drosophila member of the Meis family of homeobox genes. hth function is required for the nuclear localization of the Hox cofactor Extradenticle (EXD). We show here that there is also a post-transcriptional control of HTH by exd : exd...