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Keywords: Meis
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Journal Articles
Journal: Development
Development (2019) 146 (16): dev174706.
Published: 15 August 2019
...Dorothea Schulte; Dirk Geerts ABSTRACT MEIS transcription factors are key regulators of embryonic development and cancer. Research on MEIS genes in the embryo and in stem cell systems has revealed novel and surprising mechanisms by which these proteins control gene expression. This Primer...
Journal Articles
Journal: Development
Development (2016) 143 (2): 276–285.
Published: 15 January 2016
... forelimb by integrating developmental signals to regulate MEIS expression. Meis Mouse limb development Polycomb Proximal-distal specification RING1 Polycomb group (PcG) genes were originally identified as encoding regulators of Hox genes in Drosophila and are evolutionarily conserved...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (7): 1534–1543.
Published: 1 April 2014
... and hence robustness of limb development. If this were the case, it should be noted that only an initial pulse of FGF, enough to trigger the first PD subdivision, would be necessary for the timing mechanism to act, because our results show that after the Meis -Hoxa11 transition, continuous FGF signaling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (3): 513–518.
Published: 1 February 2013
... of distal transformation. They also have nuclear MEIS, which can act as an upper arm identity regulator, only upon upper arm amputation. By contrast, myogenic cells do not obey the rule of distal transformation and display nuclear MEIS upon amputation at any proximo-distal level. These results indicate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (5): 805–811.
Published: 1 March 2008
... RPCs throughout the period of neurogenesis in the retina, whereas Meis2 is specific for RPCs prior to the onset of retinal differentiation. Transfection of Meis-inactivating constructs impaired RPC proliferation and led to microphthalmia. RNA-interference-mediated knock-down of expression indicated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (3): 613–627.
Published: 1 February 2004
... chondrogenesis and, acting as a member of Meinox-Pbc-Hox trimers, it plays an essential role in hindbrain development. * Author for correspondence (e-mail: francesco.argenton@unipd.it ) 27 10 2003 © 2004. 2004 Vertebrate Zebrafish Hox Pbx Meis Prep Rhombomere Segmentation...
Journal Articles
Journal: Development
Development (2003) 130 (4): 741–751.
Published: 15 February 2003
..., J. and Krause, H. M. ( 1998 ). Dynamic changes in the functions of Odd-skipped during early Drosophila embryogenesis. Development 125 , 4851 -4861. Shanmugam, K., Green, N. C., Rambaldi, I., Saragovi, H. U. and Featherstone, M. S. ( 1999 ). PBX and MEIS as non-DNA-binding partners...
Journal Articles
Journal: Development
Development (2002) 129 (19): 4371–4386.
Published: 1 October 2002
... propose revising the vertebrate nomenclature to reflect phylogenetic relationships among the Dlx genes. *Author for correspondence (e-mail: gepangan@facstaff.wisc.edu ) 5 7 2002 © 2002. 2002 Distal-less Dlx extradenticle homothorax Meis Msx Pbx Antenna...
Journal Articles
Journal: Development
Development (2002) 129 (3): 585–595.
Published: 1 February 2002
...Seong-Kyu Choe; Nikolaos Vlachakis; Charles G. Sagerström Meis homeodomain proteins function as Hox-cofactors by binding Pbx and Hox proteins to form multimeric complexes that control transcription of genes involved in development and differentiation. It is not known what role Meis proteins play...
Journal Articles
Journal: Development
Development (2001) 128 (21): 4139–4151.
Published: 1 November 2001
..., and probably function by revealing the intrinsic specificity of Hox proteins. Vertebrate orthologs of Exd and Hth, known as Pbx and Meis (named for a myeloid ecotropic leukemia virus integration site), respectively, are encoded by multigene families and are present in multimeric complexes together...
Journal Articles
Journal: Development
Development (2001) 128 (18): 3405–3413.
Published: 15 September 2001
... ) 14 6 2001 © 2001. 2001 Meis Transcription Activation Homeodomain Imaginal discs Homothorax Drosophila melanogaster The epidermis and cuticle of the cephalic and thoracic segments, the appendages, and the external genitalia of the adult fly, are derived from the imaginal...
Journal Articles
Journal: Development
Development (2001) 128 (18): 3595–3607.
Published: 15 September 2001
...), expression in r5/r6 is reduced. (D,I) Reporter staining is completely abolished when both HOX/PBC sites (construct 10) are mutated. (E,J) Mutations in the Prep/Meis motif (construct 11) have no effect on reporter activity. All embryos are at 10.0 dpc. The respective constructs and mutated sites are noted...