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Keywords: Meis
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Journal Articles
Journal:
Development
Development (2019) 146 (16): dev174706.
Published: 15 August 2019
...Dorothea Schulte; Dirk Geerts ABSTRACT MEIS transcription factors are key regulators of embryonic development and cancer. Research on MEIS genes in the embryo and in stem cell systems has revealed novel and surprising mechanisms by which these proteins control gene expression. This Primer...
Journal Articles
Nayuta Yakushiji-Kaminatsui, Takashi Kondo, Takaho A. Endo, Yoko Koseki, Kaori Kondo, Osamu Ohara, Miguel Vidal, Haruhiko Koseki
Journal:
Development
Development (2016) 143 (2): 276–285.
Published: 15 January 2016
... forelimb by integrating developmental signals to regulate MEIS expression. Meis Mouse limb development Polycomb Proximal-distal specification RING1 Polycomb group (PcG) genes were originally identified as encoding regulators of Hox genes in Drosophila and are evolutionarily conserved...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2014) 141 (7): 1534–1543.
Published: 1 April 2014
... financial interests. 5 12 2013 2 2 2014 © 2014. Published by The Company of Biologists Ltd 2014 Vertebrate limb Patterning Proximo-distal Meis Hox Epigenetics Retinoic acid FGF Chick Mouse Development of the main axis of vertebrate limbs...
Includes: Supplementary data
Journal Articles
Eugen Nacu, Mareen Glausch, Huy Quang Le, Febriyani Fiain Rochel Damanik, Maritta Schuez, Dunja Knapp, Shahryar Khattak, Tobias Richter, Elly M. Tanaka
Journal:
Development
Development (2013) 140 (3): 513–518.
Published: 1 February 2013
... of distal transformation. They also have nuclear MEIS, which can act as an upper arm identity regulator, only upon upper arm amputation. By contrast, myogenic cells do not obey the rule of distal transformation and display nuclear MEIS upon amputation at any proximo-distal level. These results indicate...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2008) 135 (5): 805–811.
Published: 1 March 2008
... RPCs throughout the period of neurogenesis in the retina, whereas Meis2 is specific for RPCs prior to the onset of retinal differentiation. Transfection of Meis-inactivating constructs impaired RPC proliferation and led to microphthalmia. RNA-interference-mediated knock-down of expression indicated...
Includes: Supplementary data
Journal Articles
Gianluca Deflorian, Natascia Tiso, Elisabetta Ferretti, Dirk Meyer, Francesco Blasi, Marino Bortolussi, Francesco Argenton
Journal:
Development
Development (2004) 131 (3): 613–627.
Published: 1 February 2004
... chondrogenesis and, acting as a member of Meinox-Pbc-Hox trimers, it plays an essential role in hindbrain development. * Author for correspondence (e-mail: [email protected]) 27 10 2003 © 2004. 2004 Vertebrate Zebrafish Hox Pbx Meis Prep Rhombomere Segmentation...
Journal Articles
Engrailed cooperates with extradenticle and homothorax to repress target genes in Drosophila
Available to PurchaseMasatomo Kobayashi, Miki Fujioka, Elena N. Tolkunova, Deepali Deka, Muna Abu-Shaar, Richard S. Mann, James B. Jaynes
Journal:
Development
Development (2003) 130 (4): 741–751.
Published: 15 February 2003
... Homeodomain Transcription Repressor Cofactor Pbx Meis The engrailed (en) gene is a homeobox-containing gene crucial for the establishment and maintenance of compartment boundaries during Drosophila development (Akam,1987 ; Blair, 1995). Its homologs in mammals are important in brain and limb...
Journal Articles
Developmental functions of the Distal-less /Dlx homeobox genes
Available to Purchase
Journal:
Development
Development (2002) 129 (19): 4371–4386.
Published: 1 October 2002
... for the specification of distal leg pattern elements, and indicate that Dll regulates the expression of as yet unknown molecules required for differential affinities between proximal and distal cells. Distal-less Dlx extradenticle homothorax Meis Msx Pbx Antenna Audition Brain...
Journal Articles
Meis family proteins are required for hindbrain development in the zebrafish
Available to Purchase
Journal:
Development
Development (2002) 129 (3): 585–595.
Published: 1 February 2002
...Seong-Kyu Choe; Nikolaos Vlachakis; Charles G. Sagerström Meis homeodomain proteins function as Hox-cofactors by binding Pbx and Hox proteins to form multimeric complexes that control transcription of genes involved in development and differentiation. It is not known what role Meis proteins play...
Journal Articles
Zebrafish Meis functions to stabilize Pbx proteins and regulate hindbrain patterning
Available to Purchase
Journal:
Development
Development (2001) 128 (21): 4139–4151.
Published: 1 November 2001
..., and probably function by revealing the intrinsic specificity of Hox proteins. Vertebrate orthologs of Exd and Hth, known as Pbx and Meis (named for a myeloid ecotropic leukemia virus integration site), respectively, are encoded by multigene families and are present in multimeric complexes together...
Journal Articles
Genetic evidence for the transcriptional-activating function of Homothorax during adult fly development
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Journal:
Development
Development (2001) 128 (18): 3405–3413.
Published: 15 September 2001
...-mail: [email protected]) 14 6 2001 © 2001. 2001 Meis Transcription Activation Homeodomain Imaginal discs Homothorax Drosophila melanogaster The epidermis and cuticle of the cephalic and thoracic segments, the appendages, and the external genitalia of the adult fly...
Journal Articles
Independent regulation of initiation and maintenance phases of Hoxa3 expression in the vertebrate hindbrain involve auto- and cross-regulatory mechanisms
Available to PurchaseMiguel Manzanares, Sophie Bel-Vialar, Linda Ariza-McNaughton, Elisabetta Ferretti, Heather Marshall, Mark M. Maconochie, Francesco Blasi, Robb Krumlauf
Journal:
Development
Development (2001) 128 (18): 3595–3607.
Published: 15 September 2001
... for correspondence (e-mail: [email protected]) 22 6 2001 © 2001. 2001 Hox genes Hindbrain Segmentation Transgenic mice Chick embryos Auto/cross-regulation Pbx Meis The Hox transcription factors play important roles in regulating anteroposterior (AP) patterning in vertebrate...
Journal Articles
Regulation of Hox target genes by a DNA bound Homothorax/Hox/Extradenticle complex
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Journal:
Development
Development (1999) 126 (22): 5137–5148.
Published: 15 November 1999
... dominant phenotypes . Development 118 , 401 – 415 . 10.1242/dev.118.2.401 Bürglin , T. (1997). Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals . Nucl. Acid Res . 25 , 4173 – 4180 . 10.1093...
Journal Articles
Generation of multiple antagonistic domains along the proximodistal axis during Drosophila leg development
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Journal:
Development
Development (1998) 125 (19): 3821–3830.
Published: 1 October 1998
...Muna Abu-Shaar; Richard S. Mann ABSTRACT homothorax (hth) is a Drosophila member of the Meis family of homeobox genes. hth function is required for the nuclear localization of the Hox cofactor Extradenticle (EXD). We show here that there is also a post-transcriptional control of HTH by exd : exd...