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Keywords: Meis
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Journal Articles
Journal: Development
Development (2019) 146 (16): dev174706.
Published: 15 August 2019
...Dorothea Schulte; Dirk Geerts ABSTRACT MEIS transcription factors are key regulators of embryonic development and cancer. Research on MEIS genes in the embryo and in stem cell systems has revealed novel and surprising mechanisms by which these proteins control gene expression. This Primer...
Journal Articles
Journal: Development
Development (2016) 143 (2): 276–285.
Published: 15 January 2016
... forelimb by integrating developmental signals to regulate MEIS expression. Meis Mouse limb development Polycomb Proximal-distal specification RING1 Polycomb group (PcG) genes were originally identified as encoding regulators of Hox genes in Drosophila and are evolutionarily conserved...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (7): 1534–1543.
Published: 1 April 2014
... financial interests. 5 12 2013 2 2 2014 © 2014. Published by The Company of Biologists Ltd 2014 Vertebrate limb Patterning Proximo-distal Meis Hox Epigenetics Retinoic acid FGF Chick Mouse Development of the main axis of vertebrate limbs...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2008) 135 (5): 805–811.
Published: 1 March 2008
... RPCs throughout the period of neurogenesis in the retina, whereas Meis2 is specific for RPCs prior to the onset of retinal differentiation. Transfection of Meis-inactivating constructs impaired RPC proliferation and led to microphthalmia. RNA-interference-mediated knock-down of expression indicated...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2003) 130 (4): 741–751.
Published: 15 February 2003
... Homeodomain Transcription Repressor Cofactor Pbx Meis The engrailed (en) gene is a homeobox-containing gene crucial for the establishment and maintenance of compartment boundaries during Drosophila development (Akam,1987 ; Blair, 1995). Its homologs in mammals are important in brain and limb...
Journal Articles
Journal: Development
Development (2002) 129 (19): 4371–4386.
Published: 1 October 2002
... for the specification of distal leg pattern elements, and indicate that Dll regulates the expression of as yet unknown molecules required for differential affinities between proximal and distal cells. Distal-less Dlx extradenticle homothorax Meis Msx Pbx Antenna Audition Brain...
Journal Articles
Journal: Development
Development (2002) 129 (3): 585–595.
Published: 1 February 2002
...Seong-Kyu Choe; Nikolaos Vlachakis; Charles G. Sagerström Meis homeodomain proteins function as Hox-cofactors by binding Pbx and Hox proteins to form multimeric complexes that control transcription of genes involved in development and differentiation. It is not known what role Meis proteins play...
Journal Articles
Journal: Development
Development (2001) 128 (21): 4139–4151.
Published: 1 November 2001
..., and probably function by revealing the intrinsic specificity of Hox proteins. Vertebrate orthologs of Exd and Hth, known as Pbx and Meis (named for a myeloid ecotropic leukemia virus integration site), respectively, are encoded by multigene families and are present in multimeric complexes together...
Journal Articles
Journal: Development
Development (2001) 128 (18): 3405–3413.
Published: 15 September 2001
...-mail: [email protected]) 14 6 2001 © 2001. 2001 Meis Transcription Activation Homeodomain Imaginal discs Homothorax Drosophila melanogaster The epidermis and cuticle of the cephalic and thoracic segments, the appendages, and the external genitalia of the adult fly...
Journal Articles
Journal Articles
Journal: Development
Development (1999) 126 (22): 5137–5148.
Published: 15 November 1999
... dominant phenotypes . Development 118 , 401 – 415 . 10.1242/dev.118.2.401 Bürglin , T. (1997). Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals . Nucl. Acid Res . 25 , 4173 – 4180 . 10.1093...
Journal Articles
Journal: Development
Development (1998) 125 (19): 3821–3830.
Published: 1 October 1998
...Muna Abu-Shaar; Richard S. Mann ABSTRACT homothorax (hth) is a Drosophila member of the Meis family of homeobox genes. hth function is required for the nuclear localization of the Hox cofactor Extradenticle (EXD). We show here that there is also a post-transcriptional control of HTH by exd : exd...