... of ojoplano (opo), an uncharacterized gene whose human ortholog is associated with orofacial clefting syndrome, in the morphogenesis of epithelial tissues. Most notably,when opo is mutated in medaka fish, optic cup folding is impaired. We characterize optic cup morphogenesis in vivo and determine...

..., 10 Kent Ridge Crescent, Singapore 119260 16 9 2003 © The Company of Biologists Limited 2003 2003 Cell differentiation ES cells Medaka fish Melanocyte Mitf The mechanisms that regulate the decision of a pluripotent cell to differentiate and which lineages...