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Keywords: Mechanotransduction
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Journal Articles
Journal: Development
Development (2021) 148 (6): dev190785.
Published: 23 March 2021
...Jin Man Kim; YoungJu Jo; Ju Won Jung; Kyungpyo Park ABSTRACT The actomyosin complex plays crucial roles in various life processes by balancing the forces generated by cellular components. In addition to its physical function, the actomyosin complex participates in mechanotransduction. However...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (4): dev187302.
Published: 17 February 2020
... Mechanobiology Mechanosensation Mechanotransduction Morphogenesis How an embryo, initially consisting of a single cell, can grow and shape itself into a complex organism is a question that has been tantalising scientists for more than a century. In his 1917 opus magnum On Growth and Form the British...
Journal Articles
Journal: Development
Development (2019) 146 (24): dev183780.
Published: 13 December 2019
...Shashi Kumar Suman; Csaba Daday; Teresa Ferraro; Thanh Vuong-Brender; Saurabh Tak; Sophie Quintin; François Robin; Frauke Gräter; Michel Labouesse ABSTRACT Mechanical forces can elicit a mechanotransduction response through junction-associated proteins. In contrast to the wealth of knowledge...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (5): dev149823.
Published: 8 March 2018
... αT-catenin N-cadherin Cell adhesion Intercalated disc Actomyosin Mechanotransduction RhoA Study of the growth patterns of rodent cardiomyocytes (CMs) during the neonatal period demonstrates that CM number peaks at 4 days of age ( Li et al., 1996 ; Soonpaa et al., 1996 ). Although CM...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (23): 4271–4283.
Published: 1 December 2017
... the morphogenesis and biomechanical integrity of tendon, joint, bone and muscle, and their integration into a functional unit. Musculoskeletal development Mechanoregulation Mechanotransduction The revolution in molecular biology and the identification of signaling pathways and gene regulatory...
Journal Articles
Journal: Development
Development (2016) 143 (3): 373–386.
Published: 1 February 2016
.... Endocardium Cardiac development Hemodynamics Bmp Krüppel-like factor 2 Vegf Mechanotransduction Zebrafish Mouse The developmental origins of the endocardium have been intensely investigated, although the molecular control and the timing of endocardial cell fate specification are currently...
Journal Articles
Journal: Development
Development (2015) 142 (4): 692–701.
Published: 15 February 2015
.../j.jsb.2005.06.002 Schwartz , M. A. and DeSimone , D. W. ( 2008 ). Cell adhesion receptors in mechanotransduction . Curr. Opin. Cell Biol.   20 , 551 - 556 . 10.1016/j.ceb.2008.05.005 Selman , G. G. ( 1955 ). Studies on the forces producing neural closure in amphibia...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (19): 3793–3798.
Published: 1 October 2014
... matter in the rat cerebellum measured by scanning force microscopy . J. Biomech. 43 , 2986 - 2992 . 10.1016/j.jbiomech.2010.07.002 DuFort , C. C. , Paszek , M. J. and Weaver , V. M. ( 2011 ). Balancing forces: architectural control of mechanotransduction . Nat. Rev. Mol. Cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (15): 3069–3077.
Published: 1 August 2013
... are comparatively well understood, how mechanical input is translated into an intracellular, biochemical response (’mechanotransduction’) is currently ill defined. From the initiation of neurite growth, to the establishment of synaptic connections with a target cell, to the formation of stable neuronal...