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Keywords: Mechanobiology
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Journal Articles
Journal: Development
Development (2023) 150 (13): dev201527.
Published: 30 June 2023
... engineered hydrogels can advance our understanding of developmental biology. Hydrogels Extracellular matrix Mechanobiology In vitro culture National Institutes of Health http://dx.doi.org/10.13039/100000002 F30AG074508 National Science Foundation http://dx.doi.org/10.13039...
Journal Articles
Journal: Development
Development (2022) 149 (7): dev197947.
Published: 31 March 2022
... and Other Communication Disorders http://dx.doi.org/10.13039/100000055 R01 DC017461 Mechanobiology Sensory development Neural crest Placodes Stem cells Organoids Summary: This Review gives an overview of our current understanding of how physical forces influence developing sensory...
Journal Articles
Journal: Development
Development (2021) 148 (24): dev192914.
Published: 15 December 2021
... self-organize into trunk-like structures with neural tube and somites . Science 370 , eaba4937 . 10.1126/science.aba4937 Vianello , S. and Lutolf , M. P. ( 2019 ). Understanding the Mechanobiology of Early Mammalian Development through Bioengineered Models . Dev. Cell 48...
Journal Articles
Journal: Development
Development (2021) 148 (13): dev196519.
Published: 1 July 2021
... regulates valve development through a molecular switch potentiating BMP-pSMAD1/5-driven growth and pSer-19-MLC2-driven contractility. Mechanobiology Cardiac valve development BMP signaling MLC contractility Congenital heart defects (CHDs) are the most common birth defects and the leading...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (4): dev187302.
Published: 17 February 2020
... forces in development. Emphasising the importance of integrative approaches and theoretical simulations to obtain comprehensive mechanistic insights into complex morphogenetic processes, the meeting provided an ideal platform to discuss the concepts and methods of developmental mechanobiology in an era...
Journal Articles
In collection:
Neural development
Journal: Development
Development (2019) 146 (20): dev174318.
Published: 11 October 2019
... Mechanobiology Chick Cerebral hemispheres account for the majority of brain volume in adult humans, and abnormalities during early development can result in dramatic downstream effects. Incomplete hemisphere division, or holoprosencephaly, represents the most common, and often lethal, brain malformation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (16): dev156125.
Published: 18 May 2018
... Mechanical Multiphysiological system Mechanobiology Human ‘organs on chips’ (organ chips) are microfluidic cell culture devices with separate parenchymal and vascular compartments lined by living human cells that mimic the multicellular architecture, tissue-tissue interfaces and relevant physical...
Journal Articles
Journal: Development
Development (2017) 144 (23): 4261–4270.
Published: 1 December 2017
..., our molecular understanding of mechanobiology has advanced to explain how passive and active forces induce similar signaling cascades that drive self-renewal, migration, differentiation or a combination of these outcomes. Improvements in stem cell culture methods, materials and biophysical tools...
Journal Articles