... ). Mechanical stress inference for two dimensional cell arrays . PLoS Comput. Biol. 8 , 1 - 9 . 10.1371/journal.pcbi.1002512 Delarue , M. , Joanny , J.-F. , Jülicher , F. and Prost , J. ( 2014a ). Stress distributions and cell flows in a growing cell aggregate . Interface...

... unknown, especially in the kidney and the mammary gland. Collective migration Morphodynamics Morphogen gradients Mechanical stress Smooth muscle Summary: This Development at a Glance article highlights the conserved and divergent mechanisms that are used to construct branched tissues...

... ). It will be interesting to determine whether YAP or other known mechanotransducers play a role in spatial patterning of smooth muscle differentiation in the mouse lung. Finally, epithelial outgrowth could generate strain in the mesenchyme that leads to mechanical stress patterns that induce airway smooth muscle...

... of tenascin C synthesized in the epithelium accompany airway epithelial branching morphogenesis in the embryonic chicken lung. Jamming Tissue morphodynamics Mechanical stress Branching morphogenesis requires reciprocal signaling between the epithelium and mesenchyme in many organs, including...

.... Mechanical stress Morphogenesis Clock Morphodynamics Branching morphogenesis is a common developmental program used to create complex ramified networks of epithelial tubes that support the flow of liquid or air ( Warburton et al., 2010 ). During development of the mammalian lung, dynamic...

... interests. © 2014. Published by The Company of Biologists Ltd 2014 Pattern Tension Mechanical stress Proliferation Bifurcation Arborized epithelial networks are found ubiquitously in the organ systems of animals as diverse as insects and mammals. Such branched epithelial tubes create...

... Mechanical stress Biomechanics The intricate network of branched airways of the lung originates as a simple epithelial tube. A sequence of recursive branching events then transforms this simple tubular geometry into a complex system of airways that conduct air and promote gas exchange postnatally...

... in wing disc size regulation. We formulated several theoretical scenarios that differ with respect to whether cell rearrangements are allowed and whether cellular growth rates are dependent on mechanical stress. We then compared these scenarios with experimental data on the polygon distribution...