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Keywords: Mechanical cues
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Journal Articles

Yap/Taz-TEAD activity links mechanical cues to progenitor cell behavior during zebrafish hindbrain segmentation

In collection:
Neural development
Adrià Voltes, Covadonga F. Hevia, Carolyn Engel-Pizcueta, Chaitanya Dingare, Simone Calzolari, Javier Terriente, Caren Norden, Virginie Lecaudey, Cristina Pujades
Journal: Development
Development (2019) 146 (14): dev176735.
https://doi.org/10.1242/dev.176735
Published: 22 July 2019
... segmentation indicated that boundary cells responded to mechanical cues in a cell-autonomous manner through Yap/Taz-TEAD activity. Cell-lineage analysis revealed that Yap/Taz-TEAD boundary cells decreased their proliferative activity when Yap/Taz-TEAD activity ceased, which preceded changes in their cell fate...
View article titled, Yap&#x2F;Taz-TEAD activity links <span class="search-highlight">mechanical</span> <span class="search-highlight">cues</span> to progenitor cell behavior during zebrafish hindbrain segmentation
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Includes: Supplementary data