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Keywords: Mathematical model
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Journal Articles
Journal: Development
Development (2024) 151 (10): dev202606.
Published: 16 May 2024
.... Highlighted Article: A theoretical framework named Sevilletor shows that the clock and wavefront model with a new self-organizing region can recapitulate the oscillations and excitability observed during mouse somitogenesis. Mathematical model Self-organization Reaction-diffusion Explants Phase...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (1): dev153544.
Published: 8 January 2018
... a mathematical model and experimental data to address features controlling neural stem cell (NSC) dynamics. We show that available experimental data fit a model in which quiescent NSCs may either become activated to divide or may undergo depletion events, such as astrocytic transformation and apoptosis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (1): dev153544.
Published: 8 January 2018
... a mathematical model and experimental data to address features controlling neural stem cell (NSC) dynamics. We show that available experimental data fit a model in which quiescent NSCs may either become activated to divide or may undergo depletion events, such as astrocytic transformation and apoptosis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (3): 427–436.
Published: 1 February 2016
... formation, whereas inhibiting Bmp signaling leads to merged clusters. These dynamic changes in cluster pattern are faithfully simulated by a mathematical model of a Turing field in which an inhibitor of Bmp signaling acts as the Turing activator. In vivo , genetic interruption of Bmp signal reception...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (3): 477–485.
Published: 1 February 2015
... : Computational modelling deciphers the connections between the cell-cycle machinery and Notch signalling which govern whether neural stem cells proliferate, differentiate or enter quiescence. Cell fate decision Cell cycle control Delta-Notch signaling Mathematical model Neural stem cell Regulatory...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (19): 3637–3648.
Published: 1 October 2014
... that, in absence of Gata6, all ICM cells adopt an Epi identity. Furthermore, the analysis of Gata6 +/− embryos reveals a dose-sensitive phenotype, with fewer PrE-specified cells. These results and previous findings have enabled the development of a mathematical model for the dynamics of the regulatory network...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (1): 82–92.
Published: 1 January 2013
... Competing interests statement The authors declare no competing financial interests. 21 9 2012 © 2013. Published by The Company of Biologists Ltd Ocellus hedgehog Patterning Mathematical model Retinal determination genes Gene network Drosophila engrailed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (16): 2797–2805.
Published: 15 August 2008
... and α4 integrin expression. Based on the observed cell proliferation, chemotaxis and the timing of BMP2 and BMP7 expression, we propose a mathematical model, a reaction-diffusion system, which not only simulates feather patterning, but which also can account for the negative effects of excess BMP2...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (1991) 113 (4): 1231–1244.
Published: 1 December 1991
... mathematical model morphogenesis cell motility notochord Morphogenesis of embryonic tissues is driven by a variety of mechanisms including cell rearrangement and shape change. In many instances, directed cell movements cause tissues to extend and narrow, so called ‘convergence and extension...