... that zebrafish ( Danio rerio ) embryos lacking either maternal or paternal Cfap53, a centriolar satellite protein, arrest during the first cell cycle. Although Cfap53 is dispensable for sperm aster function, it aids proper formation of the mitotic spindle. During cell division, Cfap53 colocalizes with γ-tubulin...

... is unknown. SCT covering the villi is terminally differentiated and SCT fragments are continuously shed into the maternal circulation. Placental explants, primary trophoblast cells that can fuse in vitro and the BeWo choriocarcinoma line have been used to study the process of SCT regeneration from...

... specific maternal mRNAs to control anterior-posterior cell fates. However, it is not known how Bicc1 binds its RNA targets or how binding affects Bicc1-dependent embryogenesis. Focusing on the KH domains, we analyzed Bicc1 mutants for their ability to bind RNA substrates in vivo and in vitro . Analyses...

... Buc-GFP, accumulates at embryonic cleavage furrows. Furthermore, we show that the maternally expressed zebrafish Kinesin-1 Kif5Ba is a binding partner of Buc and that maternal kif5Ba (M kif5Ba ) plays an essential role in germline specification in vivo. Specifically, M kif5Ba is required to recruit GP...

... maternal mRNAs and proteins deposited in the egg during oocyte maturation. Although the early zebrafish embryo is competent to transcribe exogenous DNA, factors present in the embryo maintain genomic DNA in a state that is incompatible with transcription. The cell cycles of the early embryo titrate out...

...Wilhelmine N. de Vries; Alexei V. Evsikov; Bryce E. Haac; Karen S. Fancher; Andrea E. Holbrook; Rolf Kemler; Davor Solter; Barbara B. Knowles The oocyte to embryo transition in metazoans depends on maternal proteins and transcripts to ensure the successful initiation of development, and the correct...

...Ashley E. E. Bruce; Cristin Howley; Yi Zhou; Sarah L. Vickers; Lee M. Silver; Mary Lou King; Robert K. Ho Early embryonic development in many organisms relies upon maternal molecules deposited into the egg prior to fertilization. We have cloned and characterized a maternal T-box gene...

... the yolk syncytial layer of the yolk cell and the enveloping layer of the blastoderm reach the vegetal pole of the embryo. The mutations half baked, avalanche and lawine produce a novel dominant effect, termed a zygotic-maternal dominant effect: heterozygous embryos produced from heterozygous females slow...