... crest-derived enteric neuron precursors. Nat. Genet. 36 , 732 -737. * Author for correspondence (e-mail: [email protected] ) 8 9 2008 © 2008. 2008 Neural crest cells Pofut1 Sox10 Mash1 (Ascl1) Wnt1-Cre The neural crest is a pluripotent cell population...

..., but sympathetic ganglia remain small. By contrast, terminal differentiation of adrenal chromaffin cells does not occur. The transcription factors Mash1 (Ascl1), Phox2a, Gata3 and Hand2(previously dHand) control the differentiation of sympatho-adrenal precursor cells, and their deregulated expression in Insm1...

... in experiments conducted using mouse and chick that Foxn4 induces expression of delta-like 4 (Dll4) and Mash1 (Ascl1). Dll4 then signals through Notch1 to subdivide the p2 progenitor pool. Foxn4, Mash1 and activated Notch1 trigger the genetic cascade leading to V2b INs, whereas the complementary set...

... capacity to undergo neuronal differentiation, with a subset of these cells retaining characteristics of immature glial cells. * Author for correspondence (e-mail: [email protected] ) 2 11 2006 © 2007. 2007 Mash1 (Ascl1) bHLH transcription factor Spinal cord...

... ) 3 3 2006 © 2006. 2006 Asymmetric cell division Neuronal specification Spinal cord Mash1 (Ascl1) Mouse Chick The dorsal horn of the spinal cord is the first relay station for somatosensory perception. Neurons located in the dorsal horn receive and process...