...David T. Champlin; James W. Truman ABSTRACT Proliferation of neural precursors in the optic lobe of Manduca sexta is controlled by circulating steroids and by local production of nitric oxide (NO). Diaphorase staining, anti-NO synthase (NOS) immunocytochemistry and the NO-indicator, DAF-2, show...

... fasciculation. Here we demonstrate a role for fasciclin II in the guidance of migratory neurons. In the developing enteric nervous system of the moth Manduca sexta , an identified set of neurons (the EP cells) undergoes a stereotyped sequence of migration along the visceral muscle bands of the midgut prior...

...David T. Champlin; James W. Truman ABSTRACT The eye primordium of the moth, Manduca sexta , shows two different developmental responses to ecdysteroids depending on the concentration to which it is exposed. Tonic exposure to moderate levels of 20-hydroxyecdysone (20E) or its precursor, ecdysone...

...David T. Champlin; James W. Truman ABSTRACT Cell proliferation within the optic lobe anlagen is dependent on ecdysteroids during metamorphosis of the moth Manduca sexta . We use cultured tissues to show that ecdysteroids must be maintained above a sharp threshold concentration to sustain...

... nucleotide binding proteins) in regulating the migratory behavior of embryonic neurons in the enteric nervous system of the moth, Manduca sexta . During the formation of the enteric nervous system, a group of approx. 300 enteric neurons (the EP cells) participate in a precise migratory sequence, during which...

...James B. Nardi ABSTRACT In embryos of the moth Manduca sexta , the first cells that immunolabel with a monoclonal antibody to a surface epitope are the primordial germ cells. With this specific immunolabel, the migratory pathways of all primordial germ cells can be readily observed in whole mounts...

... and differentiation along the same path-ways that are formed during the preceding phases of neuronal migration. 07 10 1992 © 1993 by Company of Biologists 1993 enteric nervous system glial progenitor Manduca sexta glial differentiation cell lineage A key feature in the formation...

...Philip F. Copenhaver; Paul H. Taghert ABSTRACT The enteric nervous system (ENS) of the moth Manduca sexta is organized into two distinct cellular domains: an anterior domain that includes several small ganglia on the surface of the foregut, and a more posterior domain consisting of a branching...

...Lisa M. Nagy; Ronald Booker; Lynn M. Riddiford ABSTRACT Using sequence homology to the Drosophila Antenna-pedia gene, we isolated a homeobox-containing gene from the lepidopteran, Manduca sexta . Sequence analysis and in situ hybridizations to tissue sections suggest that the Manduca gene encodes...

...Philip F. Copenhaver*; Paul H. Taghert ABSTRACT The enteric plexus (EP) is a major division of the enteric nervous system (ENS) in the moth Manduca sexta and contains a dispersed population of about 360 bipolar neurons, the EP cells. Previously we showed that embryonic EP cells achieve their mature...

...Ronald Booker; James W. Truman ABSTRACT Octopod ( Octo ) is a mutation of the moth Manduca sexta , which results in the homeotic transformation of the ventral surface of the first (Al) and less often the second (A2) abdominal segments in the anterior direction. The extent of the transformation...

...Yoshiomi Kato; Lynn M. Riddiford ABSTRACT Temporal and regional changes in mitotic frequency were examined in the dorsal epidermis of the fourth and fifth abdominal segments of Manduca sexta during metamorphosis. Mitoses occurred only in the middle intrasegmental region, but not in the segmental...

...Yoshiomi Kato; K. K. Nair; Karen A. Dyer; Lynn M. Riddiford ABSTRACT The relative DNA content of Manduca sexta abdominal epidermal nuclei during the final larval instar was measured by cytophotometry of whole-mount preparations of the epidermis. In the middle intrasegmen-tal region, epidermal cells...