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Keywords: Mandible
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Journal Articles
Journal: Development
Development (2019) 146 (5): dev171942.
Published: 4 March 2019
..., the mandible size considerably increases through two moltings (via the presoldier stage) under the control of juvenile hormone (JH). Regulatory genes are predicted to provide patterning information that induces the mandible-specific cell proliferation. To identify factors responsible for the mandibular...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (2): dev157438.
Published: 25 January 2018
... that patterns the mandible, maxilla and intervening hinge domain, but how the genes encoding these proteins are regulated remains unclear. Herein, we demonstrate that the concerted action of the AP-2α and AP-2β transcription factors within the mouse neural crest is essential for jaw patterning. In the absence...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (6): 985–992.
Published: 15 March 2010
...Wen Sun; Weiwei Sun; Jingning Liu; Xichao Zhou; Yongjun Xiao; Andrew Karaplis; Martin R. Pollak; Edward Brown; David Goltzman; Dengshun Miao To determine whether the calcium-sensing receptor (CaR) participates in tooth formation and dental alveolar bone development in mandibles in vivo, we examined...
Journal Articles
Journal: Development
Development (2009) 136 (4): 615–625.
Published: 15 February 2009
... is largely unknown. Here, we report that Hand2 negatively regulates intramembranous ossification of the mandible by directly inhibiting the transcription factor Runx2, a master regulator of osteoblast differentiation. Hand proteins physically interact with Runx2, suppressing its DNA binding...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (18): 4413–4423.
Published: 15 September 2004
.... * Author for correspondence (e-mail: clouthier@louisville.edu ) 7 6 2004 © 2004. 2004 Mouse Bone Mandible Patterning Neural crest cell Homeobox gene Craniofacial morphogenesis is orchestrated through a specific array of transcription factors, expressed in both spatially...
Journal Articles
Journal: Development
Development (2002) 129 (18): 4347–4357.
Published: 15 September 2002
... of the phenotype is dependent on the genetic background of a C57BL/6 (B6) strain; most of the offspring of Otx2 knock-out chimeras, which are equivalent to the F 1 of CBA and B6 strains, backcrossed with B6 females display reduction or loss of mandible, whereas those backcrossed with CBA females do not show...