... assembly in male germ cells . Mol. Cell   66 , 89 - 101 e8 . 10.1016/j.molcel.2017.02.025. Bellvé , A. R. ( 1993 ). Purification, culture, and fractionation of spermatogenic cells . Methods Enzymol.   225 , 84 - 113 . 10.1016/0076-6879(93)25009-Q Bettegowda , A. and Wilkinson...

... deleted this sirtuin in male germ cells and found that mutant mice had smaller testes, a delay in differentiation of pre-meiotic germ cells, decreased spermatozoa number, an increased proportion of abnormal spermatozoa and reduced fertility. At the molecular level, mutants do not have the characteristic...

...Noriyoshi Sakai Because cell culture systems are easily accessible for experimental genetic manipulation, male germ cell culture is of great usefulness in creating sperm vectors. This report describes that cultured male germ cells of zebrafish ( Danio rerio ) underwent mitosis and transmeiotic...

... that the gene is not essential for female reproduction. Bmp8a and Bmp8b are expressed in similar patterns in male germ cells. Unlike homozygous Bmp8b tm1 mutants, homozygous Bmp8a tm1 males do not show obvious germ cell defects during the initiation of spermatogenesis. However, germ cell degeneration...