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Keywords: Macrophage
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Neural development
Journal: Development
Development (2023) 150 (9): dev201574.
Published: 28 April 2023
...-immune crosstalk. Summary: Secretion of the previously uncharacterized protein 4931414P19Rik by neural progenitors is crucial for mediating neuro-immune crosstalk and for regulating neuronal migration during brain development. Brain development Neuronal migration Microglia Macrophage...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (8): dev201510.
Published: 27 April 2023
... and repair has been documented over many decades, recent studies have begun to define a more direct role for specific immune cells in the modulation of tissue repair. One particular cell of the innate immune system, the macrophage, has emerged as a central integrator of the complex molecular processes...
Journal Articles
Journal: Development
Development (2022) 149 (8): dev200270.
Published: 3 May 2022
...Christopher Zhe Wei Lee; Florent Ginhoux ABSTRACT Although best known for their phagocytic and immunological functions, macrophages have increasingly been recognised as key players in the development, homeostasis and regeneration of their host tissues. Early during development, macrophages...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2022) 149 (8): dev199636.
Published: 26 October 2021
... injury model to investigate inflammatory and regenerative responses in larval zebrafish using heartbeat-synchronised light-sheet fluorescence microscopy. We used this model to test two clinically approved CDK9 inhibitors, AT7519 and flavopiridol, examining their effects on neutrophils, macrophages...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (12): dev187815.
Published: 17 June 2020
...Gillian J. Wilson; Ayumi Fukuoka; Samantha R. Love; Jiwon Kim; Marieke Pingen; Alan J. Hayes; Gerard J. Graham ABSTRACT Macrophages are key regulators of developmental processes, including those involved in mammary gland development. We have previously demonstrated that the atypical chemokine...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (9): dev156000.
Published: 2 May 2019
...Marine Theret; Remi Mounier; Fabio Rossi ABSTRACT The discovery of new non-canonical (i.e. non-innate immune) functions of macrophages has been a recurring theme over the past 20 years. Indeed, it has emerged that macrophages can influence the development, homeostasis, maintenance and regeneration...
Journal Articles
Journal: Development
Development (2017) 144 (21): 3907–3916.
Published: 1 November 2017
...Jennifer Simkin; Mimi C. Sammarco; Luis Marrero; Lindsay A. Dawson; Mingquan Yan; Catherine Tucker; Alex Cammack; Ken Muneoka In mammals, macrophages are known to play a major role in tissue regeneration. They contribute to inflammation, histolysis, re-epithelialization, revascularization and cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (9): 1464–1474.
Published: 1 May 2016
... of a general macrophage/microglial reaction caudal to a spinal transection in adult zebrafish . J. Comp. Neurol.   433 , 131 - 147 . 10.1002/cne.1131 Becker , C. G. and Becker , T. ( 2015 ). Neuronal regeneration from ependymo-radial glial cells - Cook, little pot, cook!   Dev. Cell   32...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2007) 134 (24): 4449–4458.
Published: 15 December 2007
...Sujata Rao; Ivan B. Lobov; Jefferson E. Vallance; Kaoru Tsujikawa; Ichiro Shiojima; Shailaja Akunuru; Kenneth Walsh; Laura E. Benjamin; Richard A. Lang Macrophages have a critical function in the recognition and engulfment of dead cells. In some settings, macrophages also actively signal programmed...
Journal Articles
Journal: Development
Development (2006) 133 (15): 2915–2924.
Published: 1 August 2006
...Sven Huelsmann; Christina Hepper; Daniele Marchese; Christian Knöll; Rolf Reuter In Drosophila embryos, macrophages originate from the cephalic mesoderm and perform a complex migration throughout the entire embryo. The molecular mechanisms regulating this cell migration remain largely unknown. We...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (20): 4955–4962.
Published: 15 October 2003
... Drosophila Hemocytes Clonal analysis Cell lineage Transplantation Blood GFP Lymph gland Macrophage Hematopoiesis The hemolymph of Drosophila contains hemocytes that either circulate freely through the body cavities or are sessile, being associated with various tissues and organs...
Journal Articles
Journal: Development
Development (2000) 127 (11): 2269–2282.
Published: 1 June 2000
... that enter tissues at different stages of development. In this paper we identify two such cell types, macrophages and eosinophils, that are recruited around the growing terminal end buds (TEBs) during postnatal development. An important role for leukocytes in mammary gland ductal outgrowth is first...
Journal Articles
Journal: Development
Development (1999) 126 (17): 3735–3745.
Published: 1 September 1999
... as in-situ hybridization for the expression of two new hemopoietic marker genes, draculin and leucocyte-specific plastin , we show that macrophages appear in the embryo at least as early as erythroid cells, but originate from ventro-lateral mesoderm situated at the other end of the embryo, just anterior...
Journal Articles
Journal: Development
Development (1999) 126 (10): 2141–2147.
Published: 15 May 1999
... and liposome-mediated macrophage elimination, we show that during regression, macrophages induce apoptosis of both pericytes and endothelial cells in a cell cycle stage-dependent manner. Target cells are signaled to die by macrophages approximately 15 hours after S-phase labeling and this corresponds...
Journal Articles
Journal: Development
Development (1997) 124 (18): 3633–3638.
Published: 15 September 1997
...Graciana Diez-Roux; Richard A. Lang ABSTRACT It is well established that macrophages have a function in scavenging apoptotic bodies from cells undergoing programmed cell death. Here we show that macrophages can also induce apoptosis of normal cells. Using injected toxic liposomes to eliminate...