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Huijuan Lin, Isabella G. Cossu, N. Adrian Leu, Aniruddha J. Deshpande, Kathrin M. Bernt, Mengcheng Luo, P. Jeremy Wang
Development (2023) 150 (9): dev201501.
Published: 12 May 2023
... for embryonic development. Here, we report that DOT1L regulates male fertility in mouse. DOT1L associates with MLLT10 in testis. DOT1L and MLLT10 localize to the sex chromatin in meiotic and post-meiotic germ cells in an inter-dependent manner. Loss of either DOT1L or MLLT10 leads to reduced testis weight...
Includes: Supplementary data