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Keywords: MIF
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Journal Articles

Mesoderm induction in Xenopus laevis . responding cells must be in contact for mesoderm formation but suppression of epidermal differentiation can occur in single cells

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K. Symes, M. Yaqoob, J. C. Smith
Journal: Development
Development (1988) 104 (4): 609–618.
https://doi.org/10.1242/dev.104.4.609
Published: 1 December 1988
... to cell while dispersion effectively dilutes the signal. In this paper, we have attempted to substitute for cell proximity by culturing dispersed blastomeres in XTC mesoderm-inducing factor (MIF). We find that dispersed cells do not respond to XTC-MIF by forming mesodermal cell types after reaggregation...
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Journal Articles

Mesoderm-inducing factors: a small class of molecules

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S. F. Godsave, H. V. Isaacs, J. M. W. Slack
Journal: Development
Development (1988) 102 (3): 555–566.
https://doi.org/10.1242/dev.102.3.555
Published: 1 March 1988
...S. F. Godsave; H. V. Isaacs; J. M. W. Slack Mesoderm-inducing factors (MIFs) from chick embryos, XTC cells and WEHI-3 cells were studied using various procedures. The object was to find whether they are similar to heparin-binding growth factors (HBGFs - the only known pure mesoderm-inducing...
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